摘要
随着生活节奏加快、饮食结构改变和社会心理因素的影响,慢性便秘的患病率呈上升趋势。慢传输型便秘(slow transit constipation,STC)是常见的慢性便秘类型。长期患病不仅严重影响患者的心理健康,还可能诱发结直肠癌、脑血管等疾病。目前临床缺乏针对性与个性化治疗,导致疗效不稳定,停药后易复发。中医辨证论治是治疗STC的一大优势,能有效改善患者的排便情况,实现个性化治疗和精准用药。通过对STC发病机制进行梳理,并对临床治疗不同证候STC的中药复方进行整理,为临床治疗STC提供了新的参考依据。
With the acceleration of the pace of life,the change of diet structure and the influence of social psychological factors,the prevalence of chronic constipation is on the rise.Slow transit constipation(STC)is a common type of chronic constipation.Long-term illness not only seriously affects the mental health of patients,but also may induce colorectal cancer,cerebrovascular diseases and other diseases.At present,the clinical lack of targeted and personalized treatment,resulting in unstable curative effect,easy to relapse after drug withdrawal.Traditional Chinese medicine(TCM)treatment based on syndrome differentiation is a major advantage in treatment of STC,which can effectively improve the defecation situation of patients and realize personalized treatment and precision medicine.Through sorting out the pathogenesis of STC,and sorting out TCM compounds for clinical treatment of STC with different syndromes,it provides a new reference for clinical treatment of STC.
作者
刘睿婷
樊薛津
金博文
尹清晟
郭虹
庄朋伟
LIU Ruiting;FAN Xuejin;JIN Bowen;YIN Qingsheng;GUO Hong;ZHUANG Pengwei(Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;School of Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Haihe Laboratory of Modern Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)
出处
《中草药》
CSCD
北大核心
2024年第23期8269-8277,共9页
Chinese Traditional and Herbal Drugs
基金
天津市科技创新基地建设项目(24ZYJDSY00280)。
关键词
慢传输型便秘
中医证型
辨证论治
中药复方
慢性便秘
slow transit constipation
traditional Chinese medicine syndrome type
syndrome differentiation and treatment
traditional Chinese medicine compound
chronic constipation
作者简介
刘睿婷,硕士研究生,研究方向为中药药理学。E-mail:l13820768854@163.com;通信作者:郭虹,副研究员,博士生导师,从事中药防治脑血管病及时间药理研究。E-mail:cacti1983@163.com;通信作者:庄朋伟,教授,博士生导师,从事中药药理学研究。E-mail:zhuangpengwei@163.com。
