摘要
见血清是兰科羊耳蒜植物,其药用历史悠久,具有清热解毒、凉血止血、消癥止痛之功效,用于吐血,咯血,肠风下血,血崩等病症。基于中药质量标志物(Q-marker)理论,从见血清的中药药性、传统功效、化学成分、现代药理作用等多个方面对见血清的Q-marker进行预测。初步确定见血清的生物碱类、菲类、黄酮类可作为主要的Q-marker,为建立和完善见血清的质量控制及评价方法提供依据。
Liparis nervosa is a plant of Liparis L.C.Rich(Orchidaceae),with a long medicinal history.It has the effects of clearing heat and detoxifying,cooling the blood and stopping bleeding,and relieving symptoms and pain.It is used for vomiting blood,hemoptysis,intestinal subwind blood,blood avalanche and other diseases.The chemical composition of L.nervosa mainly includes alkaloids,benzoates,phenanthrene,dihydrophenanthrenes and biphenanthrenes,which have antihyperuric,haemostatic and anticancer effects.This paper reviews and summarizes the chemical composition and pharmacological effects of L.nervosa.Based on the five principles of Chinese medicine quality markers(Q-Marker),this study predicts the Q-Marker of L.nervosa from various aspects such as traditional Chinese medicine properties of,conventional effects,and modern pharmacological effects of L.nervosa.It is preliminarily determined that alkaloids,phenanthrenes and flavonoids can be used as the main Q-markers of L.nervosa,which provides a basis for establishing and improving the quality control and evaluation methods of L.nervosa.
作者
马艺宁
梁盼
杨露银
蒲清荣
董艳丽
毛琳慎
任维
杨思进
MA Yining;LIANG Pan;YANG Luyin;PU Qingrong;DONG Yanli;MAO Linshen;REN Wei;YANG Sijin(Southwest Medical University,Luzhou 646000,China;The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University,Luzhou 646000,China)
出处
《世界中医药》
CAS
北大核心
2024年第6期893-898,903,共7页
World Chinese Medicine
基金
国家中医药管理局创新团队和人才培养计划项目(ZYYCXTD-C-202207)
四川省中医药管理局2020年度花椒药用价值研发专项(2020HJZX004)--创新中药“茜花痛风胶囊”临床前研究
泸州市科技计项目(2022-RCM-172)--基于质量标志物(Q-marker)的茜花痛风胶囊治疗痛风精准质控成分辨识研究。
关键词
见血清
研究现状
化学成分
药理作用
质量标志物
产地、药性
传统功效
Liparis nervosa
Research status
Chemical components
Pharmacological effects
Q-Marker
Origin
Medicinal properties
Conventional effects
作者简介
马艺宁(1997.01-),女,硕士研究生在读,研究方向:中西医结合防治心脑血管疾病,E-mail:20210399120027@stu.swumu.edu.cn;通信作者:杨思进(1962.04-),男,博士,教授,博士研究生导师,研究方向:中西医结合防治心脑疾病,E-mail:ysjimn@swmu.edu.cn。
