摘要
慢性心力衰竭(CHF)是多种心血管疾病的终末阶段。中医认为CHF多属本虚标实,病机关键是心肾阳虚。心气虚日久累及心阳,心阳虚贯穿整个病理过程;辨证可分为阳虚血瘀证、阳虚水泛证、心肾阳虚证、阳气虚脱证;治则重在益气温阳。附子为温阳要药,药性刚燥,走而不守,上助心阳以通脉,故在使用温阳法治疗CHF时,多取附子,回阳救逆,常配伍人参、黄芪、干姜、桂枝、甘草等增强补阳功效。本文查阅近年相关文献,重点综述附子及其常用药对治疗CHF的临床应用及机制研究进展,并分析现代医家治疗CHF的临证经验,以期为中医临床治疗CHF提供指导和帮助。
Chronic heart failure(CHF)is the terminal stage of many cardiovascular diseases.Traditional Chinese medicine(TCM)believes that the pattern type of CHF is mostly deficiency in the root and excess in the tip,and yang deficiency of the heart and kidney is the key pathogenesis.Long time heart qi deficiency affects heart yang,and heart yang deficiency runs through the whole pathological process.There are yang deficiency and blood stasis syndrome,yang deficiency and water flooding syndrome,heart and kidney yang deficiency syndrome and yang qi collapse syndrome in syndrome differentiation of this condition.The treatment,therefore,is usually focused on replenishing qi and warming yang.Fu Zi(Radix aconiti lateralis preparata),an important medicine for warming yang,is rigid dry in nature,and is good at moving around the body without sticking to a particular location,and therefore,can assist heart yang and unblock vessels.Therefore,in the treatment of CHF using warming yang method,radix aconiti lateralis preparata is mostly used.This treatment is to take its function of restoring yang to save from collapse.Radix aconiti lateralis preparata is often used by combining with other medicinals,such as Ren Shen(radix ginseng),Huang Qi(radix astragali seu hedysari),Gan Jiang(rhizoma zingiberis),Gui Zhi(ramulus cinnamomi),and Gan Cao(radix glycyrhizae),to enhance its effect of replenishing Yang.In order to provide guidance and help for the clinical treatment of CHF,the authors reviewed the clinical application research and mechanism research progress of radix aconiti lateralis preparata and other commonly used medicinals related in recent years,and analyzed the clinical practice and prescription of modern physicians in treating CHF.
作者
冯兰栓
宁博
王一鸣
余湖斌
赵明君
FENG Lanshuan;NING Bo;Wang Yiming;Yu Hubin;ZHAO Mingjun(Shaanxi University of Chinese Medicine,Xianyang 712000,China;Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China)
出处
《中医药学报》
2024年第1期109-115,共7页
Acta Chinese Medicine and Pharmacology
基金
国家重点研发计划-中医药现代化研究重点专项(2018YFC1704204)
陕西省省级院士工作站建设项目-吴以岭院士工作站(陕组通字﹝2019﹞49号-30)
陕西省名中医赵明君传承工作室建设项目(2019007)
陕西省教育厅重点实验室项目(22JS005)
陕西省重点研发计划项目(2017SF-277)
陕西省科协项目(2021PSL99)
陕西中医药大学附属医院科研课题计划项目(2020YSGZZ001)。
关键词
慢性心力衰竭
附子
药对
研究进展
Chronic Heart Failure(CHF)
Radix aconiti lateralis preparata
Medicinal couplet
Research progress
作者简介
冯兰栓(1998-),女,硕士研究生,研究方向:中西医结合防治心血管疾病的基础与研究;通讯作者:赵明君(1964-),男,教授,主任医师,硕士研究生导师,陕西省名中医,国家中医药管理局心血管重点专科学科带头人,研究方向:中西医结合防治心血管疾病的基础与研究。
