摘要
升麻始载于《神农本草经》,列为上品,是我国传统发散风热类中药。近年来国内外学者对升麻各方面研究逐渐深入,其新的化学成分与药理作用不断被发现。通过查阅文献,在对其化学成分与药理作用进行总结的基础上,根据质量标志物的定义,从生源途径、药效、传统药性、不同配伍中显效成分几个方面对升麻的质量标志物进行预测,为升麻质量评价研究提供科学依据。
Cimicifugae Rhizoma is contained in the "Shen Nong’s Herbal Classic" and listed as the top grade. It is a traditional Chinese medicine for divergent wind and heat. In recent years, scholars have gradually deepened their research on various aspects of Cimicifugae Rhizoma, and its new chemical components and pharmacological effects have been discovered. Based on the review of the literature, the summary of its chemical composition and pharmacological effects, according to the definition of Q-marker, from the aspects of the source route, drug efficacy, traditional drug properties, and the significant components in different compatibility, the Q-marker of Cimicifugae Rhizoma is predicted, in order to provide a scientific basis for the quality evaluation of Cimicifugae Rhizoma.
作者
黄广欣
龚苏晓
许浚
姚奕
张铁军
刘昌孝
HUANG Guang-xin;GONG Su-xiao;XU Jun;YAO Yi;ZHANG Tie-jun;LIU Chang-xiao(Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;National&Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine,Tianjin 300301,China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine,Tianjin 300301,China;State Key Laboratory of Drug Delivery and Pharmacokinetics,Tianjin Institute of Pharmaceutical Research,Tianjin 300301,China)
出处
《中草药》
CAS
CSCD
北大核心
2020年第10期2651-2660,共10页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(81830111)
国家自然科学基金资助项目(81703802)
“中医药现代化研究”重点专项(2019YFC1711200)资助项目。
关键词
升麻
化学成分
药理作用
质量评价
质量标志物
Cimicifugae Rhizoma
chemical compositions
pharmacological effects
quality evaluation
Q-marker
作者简介
黄广欣(1995-),男,硕士研究生,主要从事中药质量研究。Tel:13163075082,E-mail:guaxin0118@163.com;通信作者:刘昌孝,中国工程院院士。E-mail:liuchangxiao@163.com;通信作者:张铁军,研究员,主要从事中药资源、中药质量研究。E-mail:zhangtj@tjipr.com。
