摘要
人参是传统的名贵中药,其主要活性成分为人参皂苷,对心血管、肿瘤、中枢神经系统等疾病有显著的疗效。特别是原人参三醇(PPT)型皂苷Rh_1具有良好的抗炎、抗过敏、提高记忆力等活性。人参皂苷Rh_1仅微量地存在于人参、三七、西洋参中。生物转化方法制备稀有人参皂苷已成为一种有效的途径。综述利用生物转化方法对PPT型人参皂苷进行转化,生成稀有人参皂苷的研究进展,以期为稀有人参皂苷的进一步开发利用提供参考。
Ginseng is a traditional medicine in Asian countries. Ginsenoside has the main active ingredient, exhibit cardiovascular, tumor, and central nervous system activities. In particular, protopanaxatriol-type ginsenosides Rh_1, exhibits anti-inflammatory, anti-allergic, and memory improvement activities. Ginsenoside Rh_1 is only found in trace amounts in Panax ginseng, Panax pseudoginseng var. notoginseng, and Panax quinquefolius. Biotransformation of rare ginsenosides has become an effective way. In this paper, the research progress of transformation of ginsenoside saponins by biotransformation to produce rare ginsenoside Rh_1 is reviewed, which provides a useful reference for the further development and preparation of ginsenoside Rh_1.
出处
《中草药》
CAS
CSCD
北大核心
2017年第19期4120-4125,共6页
Chinese Traditional and Herbal Drugs
基金
长白山学者特聘教授专项资金(00566)
关键词
原三醇型皂苷
生物转化
人参皂苷RH1
抗炎活性
抗过敏活性
protopanaxatriol ginsenoside
biotransformation
ginsenoside Rh1
anti-inflammatory activity
anti-allergic activity
作者简介
毕云枫（1976-），男，副教授，研究方向为食品酶学研究。Tel：（0431）84533239 E—mail：781310113@qq．com
通信作者刘景圣（1964-），男，博士生导师，教授，研究方向为粮食深加工与功能性食品研究。E-mail：Liujs1007@vip．sina．com.cn
