摘要
目的:研究蒙药蒙古莸的化学成分。方法:采用硅胶柱色谱和制备型高效液相色谱等技术对蒙古莸醇提物的化学成分进行分离纯化,再利用波谱技术结合文献报道鉴定化合物的结构。结果:从蒙古莸地上部分醇提物的石油醚萃取物中分离得到12个化合物,分别鉴定为:taxodione(1)、ferruginol(2)、huperphlegmarin B(3)、caryopterisoid Q(4)、6α,11,12,15-tetrahydroxy-8,11,13-abietatrien-7-one(5)、α-tocopherolquinone(6)、hexadeca-9,13-diensaeureethylester(7)、邻苯二甲酸二丁酯(8)、1,6-己内酰胺(9)、phytyl hexadecanoate(10)、豆甾醇(11)、β-谷甾醇(12)。结论:其中,化合物5~11为首次从该植物中分离得到。
Objective:To study the chemical constituents of Mongolian medicine Caryopteris mongholica.Methods:The chemical constituents from the ethanol extract of Caryopteris mongholica were isolated and purified by silica gel column chromatography and prepaved high performance liquid chromatography.The structures of the compounds were identified by spectral technique and combined with literature reports.Results:Twelve compounds were isolated from the petroleum ether extract of the ethanol extract of above ground part of Caryopteris mongholica and identified as taxodione(1)、ferruginol(2)、huperphlegmarin B(3)、caryopterisoid Q(4)、6α,11,12,15-tetrahydroxy-8,11,13-abietatrien-7-one(5),α-tocopherolquinone(6),hexadeca-9,13-diensaeureethylester(7),dibutyl phthalate(8),1,6-hexalactam(9),phytyl hexadecanoate(10),stigmasterol(11),β-sitosterol(12),respectively.Conclusion:Among them,compounds 5 to 11 are isolated from Caryopteris mongholica for the first time.
作者
代那音台
邰巴达拉胡
孙天霞
Dainayintai;Taibadalahu;SUN Tian-xia(Key Laboratory of Mongolian Medicine R&D Engineering,Ministry of Education,Inner Mongolia University for Nationalities,Tongliao 028000,China;Jilin Institute of Ginseng Science,Changchun University of Chinese Medicine,Changchun 130117,China)
出处
《中药材》
CAS
北大核心
2023年第12期3010-3013,共4页
Journal of Chinese Medicinal Materials
基金
内蒙古自治区高等学校科学研究项目(NJZY22457)
2023年内蒙古自治区直属高校基本科研业务费项目(GXKY23Z013)
蒙医药研发工程教育部重点实验室开放课题(MDK2022039)。
关键词
蒙古莸
化学成分
Caryopteris mongholica Bunge
Chemical constituents
作者简介
代那音台(1988-),男,博士,实验师,研究方向:蒙药药效物质基础及作用机制,E-mail:dainayintai@126.com;通讯作者:孙天霞,E-mail:15844014726@163.com。
