摘要
当归是我国药食同源的主要中药材之一,具有补血活血、调经止痛、润肠通便的功效,主产地为甘肃东南部,尤以甘肃岷县的“岷归”驰名中外。当归中的化学成分主要包括挥发油类、有机酸类和多糖类成分,具有抗炎镇痛、抗肿瘤、抗氧化、免疫调节等药理作用,临床应用极为广泛。该文结合国内外相关文献,对当归各类炮制品化学成分和药理作用的研究现状进行了系统的综述及展望,以期为当归今后的研究、临床应用以及相关药品的开发提供理论上的参考和支持。
Angelicae Sinensis Radix is one of the main Chinese medicinal materials with both medicinal and edible values.It has the functions of tonifying and activating blood,regulating menstruation and relieving pain,and moistening intestines to relieve constipation.It is mainly produced in the southeastern Gansu province,and that produced in Minxian,Gansu is praised for the best quality.The chemical components of Angelicae Sinensis Radix mainly include volatile oils,organic acids,and polysaccharides,which have anti-inflammatory,pain-relieving,anti-tumor,anti-oxidation,immunomodulatory and other pharmacological effects.Therefore,this medicinal material is widely used in clinical practice.By reviewing the relevant literature,this study systematically introduced the research status about the chemical constituents and pharmacological effects of processed Angelicae Sinensis Radix products,aiming to provide a theoretical reference and support for the future research,development,and clinical application of related drugs.
作者
马燕
张育贵
石露萍
柳军玺
余琰
MA Yan;ZHANG Yu-gui;SHI Lu-ping;LIU Jun-xi;YU Yan(Gansu University of Chinese Medicine,Lanzhou 730000,China;Northwest Key Laboratory of Chemistry of Characteristic Plant Resources/Gansu Key Laboratory of Natural Medicine,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2023年第22期6003-6010,共8页
China Journal of Chinese Materia Medica
基金
甘肃省中医药研究中心2019—2020年度甘肃省中药质量与标准研究重点实验室开放课题(zyzx-2020-29)
甘肃省科技厅揭榜挂帅项目(21ZD2JA004)
国家自然科学基金地区科学基金项目(82160750)。
关键词
当归
炮制方法
化学成分
药理作用
Angelicae Sinensis Radix
processing method
chemical component
pharmacological effect
作者简介
通信作者:余琰,博士,副教授,硕士生导师,研究方向为中药新剂型与新技术、新工艺,E-mail:lzdxyuyan@126.com;马燕,硕士研究生,E-mail:2821632311@qq.com。
