摘要
为客观、定量分析中药川芎的研究现状和热点,为今后深入研究和临床应用提供指导。检索Web of Science、PubMed、Medline、中国知网(CNKI)、维普(VIP)、万方(Wanfang)、中国生物医学文献服务系统(SinoMed)等7个数据库,2010—2023年中药川芎的研究文献。采用NoteExpress文献管理器和人工阅读完成文献数据的筛选,分析年发文量和发文期刊。使用CiteSpace软件对研究机构、作者和关键词等进行系统分析,绘制相关知识图谱。经过筛选,纳入中文文献1137篇,英文433篇,年发文量均呈增长趋势。《中国实验方剂学杂志》《Journal of Ethnopharmacology》分别是发文量最多的中、英文期刊;中、英文文献发表最多的机构分别为成都中医药大学和南京中医药大学;彭成和FENG Yi等作者中、英文发文量较多。对中、英文关键词分析发现,阿魏酸、信号通路、机制、头痛、川芎嗪和细胞凋亡等关键词出现频率较高;共产生20个聚类和30个突现词。经综合分析,发现该领域研究趋势和热点主要集中在药理成分及分离、药理作用及机制、临床应用及疗效、药对配伍及功效、质量评价与控制、栽培种植及改良等6个方面。
This study aims to objectively and quantitatively analyze the research status and hot spots of Chuanxiong Rhizoma and provide guidance for further research and clinical application of this herbal medicine.Firstly,the research articles involving Chuanxiong Rhizoma from 2010 to 2023 were retrieved from seven databases including Web of Science,PubMed,Medline,CNKI,VIP,Wanfang,and SinoMed.Then,NoteExpress and manual reading were employed to complete the de-duplication and screening of the articles,and the annual number of publications and journals was analyzed.Finally,CiteSpace was used for systematic analysis of the research institutions,authors,and keywords,and the corresponding knowledge maps were established.After screening,1137 articles in Chinese and 433 articles in English were included,and the annual number of publications showed an increasing trend.Chinese Journal of Experimental Traditional Medical Formulae and Journal of Ethnopharmacology were the top Chinese and English journal in the number of publications.Chengdu University of Traditional Chinese Medicine and Nanjing University of Chinese Medicine published the most articles in Chinese and English,respectively.PENG Cheng and FENG Yi were the authors published more articles in Chinese and English.Ferulic acid,signaling pathway,mechanism,headache,ligustrazine,and apoptosis were frequent keywords.A total of 20 clusters and 30 bursts were generated.The comprehensive analysis showed that the research trends and hot spots in this field mainly focused on pharmacological components and isolation,pharmacological effects and mechanism,clinical application and efficacy,compatibility and efficacy of drug pairs,quality evaluation and control,and cultivation and germplasm improvement.
作者
廉坤
叶嘉豪
李鑫
胡志希
李琳
LIAN Kun;YE Jia-hao;LI Xin;HU Zhi-xi;LI Lin(Hunan University of Chinese Medicine,Changsha 410208,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2023年第17期4789-4797,共9页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(82274412)
广东省重点领域研发项目(2020B1111100001)。
关键词
川芎
药理作用
质量评价
临床应用
文献计量学
Chuanxiong Rhizoma
pharmacological effect
quality evaluation
clinical application
bibliometrics
作者简介
廉坤,硕士研究生,E-mail:2803146053@qq.com;通信作者:胡志希,博士,教授,博士生导师,研究方向为中医药客观化及心血管疾病本质与诊治规律,E-mail:003405@hnucm.edu.cn。
