摘要
目的:观察虎符铜砭刮痧联合抗病毒治疗乙型肝炎肝硬化代偿期瘀血阻络证的临床疗效。方法:采用随机数字表法将80例患者分为对照组和观察组,每组各40例。对照组患者采用恩替卡韦抗病毒治疗,观察组患者在对照组的基础上加用虎符铜砭刮痧,每7天1次,4次一个疗程,连续3个疗程,共治疗12次。观察治疗前后患者肝功能指标、中医证候评分、舌下络脉变化、生活质量评分、肝硬度值等指标的变化。结果:两组患者中医证候积分、舌下络脉积分、生活质量评分、肝硬度值、ALT、AST均较治疗前明显改善(P<0.05)。观察组患者中医证候积分、肝硬度值、生活质量评分均较对照组患者明显改善(P<0.05),ALT、AST两组比较无统计学意义(P>0.05)。在胁痛、腹胀、纳差、乏力、舌象、舌下络脉等中医症状的改善上,观察组患者较对照组具有明显差异(P<0.05)。结论:虎符铜砭刮痧联合恩替卡韦治疗能明显改善乙型肝炎肝硬化代偿期瘀血阻络证患者的中医症状、舌下络脉淤血、肝硬度值、ALT、AST水平及生活质量。
Objective:To evaluate the efficacy of HufuTongbianscraping combined with antiviral therapy on patients with compensated hepatitis B cirrhosis differentiated into Yuxuezuluo syndrome.Methods:Atotal of 80 patients with compensated hepatitis B cirrhosis were divided into control group and observation group by random number table method, with 40 cases in each group. Patients in control group were treated with entecavir anti-HBV therapy, and the observation group were treated with HufuTongbianscraping on the basis of the control group once every 7 days, 4 times a course for 3 consecutive courses, 12 times in total. The changes of TCM symptom score, sublingual collaterals and quality of life score before and after treatment were observed. Results:The scores of TCM syndromes, sublingual collaterals, life quality, liver hardness, ALT and AST of the two groups were significantly improved compared with those before treatment(P<0.05).Compared with the control group, TCM syndrome, liver hardness and quality of life in the observation group were significantly improved(P<0.05), There was no significant difference in ALT and AST between the two groups(P>0.05).Compared with the control group, the patients in the obsevvation group had significant clifference in the improvement of TCM symptons such as hypochondriac pain, abdominal distension, anorexia, fatigue, tongue image and sublingual collaterals(P<0.05). Conclusion:Hufu Tongbian scraping combined with entecavir could significantly improve the TCM syndrome group, sublingual collateral congestion, liver hardness, alt, AST and quality-life of patients with blood stasis obstructing collaterals during compensatory period of hepatitis B cirrhosis.
作者
陈茜
段玉薇
李梦荷
周铖
赵晨露
张丽慧
费景兰
CHEN Qian;DUAN Yu-wei;LI Meng-he;FEI Jing-lan(Department of Gastroenterology,The First Affiliated Hospital of Henan University of Chinese medicine(Zhengzhou Henan,450000)China;不详)
出处
《中西医结合肝病杂志》
CAS
2022年第6期490-493,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
河南省中医药科学研究专项课题(No.2018ZY2129)
河南省第二批国家临床研究基地科研专项课题(No.2019JDZX2059)。
关键词
虎符铜砭刮痧
乙型肝炎肝硬化代偿期
中医药
Hu fu Tong bian scraping
compensatory stage of hepatitis B cirrhosis
traditional Chinese medicine
作者简介
通讯作者:费景兰,E-mail:yifuyuanxiaohua@163.com。
