摘要
罗汉果为葫芦科植物罗汉果Siraitia grosvenorii的干燥果实,是一种主产于广西的道地中药,也是药食两用药材。研究表明其含有罗汉果苷、黄酮类、多糖类、蛋白质及氨基酸、油脂类等多种化合物,且具有润肺止咳、润肠通便、调节糖脂代谢、保肝、抗肿瘤等多种药理活性。对罗汉果的化学成分和药理作用进行总结,并对其质量标志物(quality marker,QMarker)进行分析预测,为罗汉果进一步的开发利用提供科学依据。
Siraitiae Fructus is the dried fruit of Siraitia grosvenorii,a Cucurbitaceae plant.It is a genuine traditional Chinese medicine mainly produced in Guangxi,also a medicinal and edible herb.Studies have shown that it contains a variety of compounds such as mogroside,flavonoids,polysaccharides,protein,and amino acids,oils,and so on.It has many pharmacological activities such as moistening lung and relieving cough,moistening intestines and defecating,regulating glycolipid metabolism,protecting liver,and anticancer.In this paper,the chemical constituents and pharmacological effects of Siraitiae Fructus are summarized,and the quality markers(Q-Marker)are analyzed and predicted to provide scientific basis for further development and utilization of Siraitiae Fructus.
作者
唐昀彤
侯小涛
杜正彩
郝二伟
张铁军
邓家刚
TANG Yun-tong;HOU Xiao-tao;DU Zheng-cai;HAO Er-wei;ZHANG Tie-jun;DENG Jia-gang(Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica,Nanning 530200,China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues,Nanning 530200,China;Tianjin Key Laboratory of Quality Markers of Traditional Chinese Medicine,Tianjin 300462,China;College of Pharmacy,Guangxi University of Chinese Medicine,Nanning 530200,China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine,Guangxi University of Chinese Medicine,Nanning 530200,China;Tianjin Institute of Pharmaceutical Research,Tianjin 300462,China)
出处
《中草药》
CAS
CSCD
北大核心
2021年第9期2843-2850,共8页
Chinese Traditional and Herbal Drugs
基金
中国-东盟传统药物研究国际合作联合实验室建设(二期)新中心建设项目(CICAR2017-Z1)
广西重点实验室建设项目(19-050-39)
广西中药药效研究重点实验室
广西科技计划项目(桂科AD19110165)
广西科学研究与技术开发计划项目(桂科AD17195025)
广西中医药大学2020年研究生教育创新计划项目(YCSZ202000)。
关键词
罗汉果
质量标志物
罗汉果苷
罗汉果苷ⅡE
罗汉果苷ⅢE
罗汉果苷ⅣE
11-氧化罗汉果苷ⅡE
山柰苷
润肺止咳
Siraitia grosvenorii(Swingle)C.Jeffrey ex A.M.Lu et Z.Y.Zhang
quality marker
mogroside
mogrosideⅡE
mogrosideⅢE
mogrosideⅣE
11-O-mogrosideⅡE
kaempferitrin
moistening lung and relieving cough
作者简介
唐昀彤(1995-),女,天津人,硕士研究生,研究方向为中药理论与药效筛选。Tel:13682196791 E-mail:2690965281@qq.com;并列第一作者:侯小涛,女,博士生导师。Tel:13878858205 E-mail:xthou@126.com;通信作者:张铁军,硕士生导师,研究员。Tel:(022)23006848,E-mail:zhangtj@tjipr.com;通信作者:邓家刚,博士生导师,教授,主要从事中药基础理论与药效筛选研究。E-mail:dengjg53@126.com。
