摘要
痰热清注射液具有清热、化痰、解毒的功效,主要含有氨基酸类、环烯醚萜类、黄酮类、苯乙醇苷类、甾体类等化学成分,具有抗炎、抗菌、抗病毒、抑制肝损伤等药理活性。近年来,国内外学者对痰热清注射液做了大量的研究工作。对其化学成分、药理活性及临床应用进行综述,以期为痰热清注射液的进一步研究提供参考。
Tanreqing Injection has the functions of clearing heat,resolving phlegm and detoxifying.It mainly contains amino acids,iridoids,flavonoids,phenylethanoid glycosides,steroids and other chemical components.Studies show that Tanreqing Injection has many pharmacological activities such as anti-inflammation,anti-bacteria,anti-virus,inhibition of liver injury and etc.Numerous domestic and foreign research efforts have been focused on the study of Tanreqing Injection.This paper comprehensively reviewed the recent progress in research on chemical constituents,pharmacological actions and clinical application of Tanreqing Injection,so as to provide some reference for its further study.
作者
王亮
陶玉龙
陈万生
WANG Liang;TAO Yu-long;CHEN Wan-sheng(Institute of Chinese Materia Medica,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China)
出处
《中草药》
CAS
CSCD
北大核心
2020年第12期3318-3328,共11页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金重点项目(81830109)。
关键词
痰热清注射液
氨基酸类
环烯醚萜类
黄酮类
苯乙醇苷类
抗炎
抗菌
抗病毒
抑制肝损伤
Tanreqing Injection
amino acids
iridoids
flavonoids
phenylethanoid glycosides
anti-inflammation
antibacterial
antiviral
inhibition of liver injury
作者简介
王亮(1988—),男,上海人,博士生在读,研究方向为中药注射剂代谢和中药化学。E-mail:15102164592@163.com;通信作者:陈万生,主任药师,教授,博士生导师,研究方向为中药药效物质研究和临床药学。Tel:(021)81886181,E-mail:chenwansheng@smmu.edu.cn。