摘要
目的探讨功能性消化不良(FD)和神经精神心理因素共病的影响因素。方法选取2012年3月至2015年9月广东省化州市人民医院收治的FD患者132例,根据焦虑、抑郁患病情况分为FD组和共病组。比较两组患者的汉密尔顿抑郁量表(HAMA)评分、汉密尔顿焦虑量表(HAMD)评分,对两组患者的临床资料进行分析。结果 FD组患者的HAMA、HAMD评分分别为(12.54±5.69)分、(13.11±5.27)分;共病组患者的HAMA、HAMD评分分别为(19.83±3.25)分、(20.05±4.13)分,差异有统计学意义(P<0.05)。两组患者的年龄、性别、病程、BMI、婚姻状况、遗传史、负性生活事件、生活质量评分及合并其他功能性胃肠病比较,差异有统计学意义(P<0.05)。对单因素分析中有统计学意义的指标进行多因素Logistic回归分析,结果显示年龄、婚姻状况、负性生活事件、生活质量评分及合并其他功能性胃肠病是影响FD和焦虑、抑郁共病的独立危险因素。结论 FD与神经精神心理障碍的共病率较高,其中患者年龄、婚姻状况、负性生活事件、生活质量评分及合并其他功能性胃肠病是影响FD和焦虑、抑郁共病的独立危险因素。
Objective To investigate the factors affecting the common disease of functional dyspepsia （FD） and mental fac- tors. Methods We selected 132 FD patients treated at Guangdong province people＇s hospital from March 2012 to September 2015. Then all cases were divided into FD group and comorbid group. The Hamilton depression scale （HAMA） score, Hamilton anxiety scale （HAMD） scores,clinical data of two groups were analysed. Results The scores of HAMA and HAMD in FD group were 12. 54±5.69 and 13.11±5.27. The HAMD and HAMA scores in the comorbid group were 19.83±3.25 and 20.05±4.13,the difference was statistically significant （P〈 0.05）. The age, gender, course of disease, BMI, marital status, genetic history, negative life events,life quality score,and other FGIDs were statistically significant different between the two groups（P〈0.05）. Multivari- ate Logistic regression analysis showed that age, marital status, negative life events, quality of life score and other FGIDs were inde- pendent risk factors. Conclusion The comorbidity rate of FD and neuropsychological disorders are high. Age,marital status,nega- tive life events,quality of life score and other FGIDs are independent risk factors.
出处
《重庆医学》
CAS
北大核心
2016年第23期3220-3222,共3页
Chongqing medicine
基金
国家自然科学基金资助项目(30971357)
关键词
消化不良
精神病状态评定量表
抑郁
焦虑
功能性消化不良
共病
dyspepsia
psychiatric status rating scales
depression
anxiety
functional dyspepsia
comorbidity
作者简介
陈锋文（1978-），副主任医师，本科，主要从事临床内科疾病方面研究。
通讯作者，E-mail：zwj623@163．com。
