摘要
利用MTT法检测景天属三种植物药垂盆草、佛甲草及凹叶景天的乙酸乙酯和正丁醇提取部位及总黄酮提取物对人肝癌细胞株HepG2、人食管癌细胞株EC109及人结肠癌细胞株SW480的体外增值抑制作用.结果表明,三种植物药的乙酸乙酯和正丁醇提取部位及总黄酮提取物都有显著的抗肿瘤作用,且各植物药总黄酮提取物的抗肿瘤活性最强.
The inhibitory activities of the the different extract fractions and total flavones of the 3 Sedum plant drugs on cancer cells proliferation of liver,esophageal and colon(HepG2,EC109,SW480)were tested by MTT assay.The results showed that the growth and proliferation of the 3 cancer cells were all significantly inhibited by ethyl acetate,n-butanol fractions and the total flavonoids of the 3 medicines.And the total flavonoid portions of the 3 medicines had the strongest anti-tumor activities.
出处
《中央民族大学学报(自然科学版)》
2011年第2期88-92,共5页
Journal of Minzu University of China(Natural Sciences Edition)
基金
湖北省自然科学基金项目(No.2009CDB419)
关键词
垂盆草
佛甲草
凹叶景天
MTT法
抗肿瘤活性
Sedum sarmentosum Bunge
Sedum lineare Thunb.
Sedum erythrostictum Migo
MTT assay
anti-tumor activities
作者简介
陈雨洁(1986-),女(汉族),山东淄博人,中南民族大学药学院硕士研究生,研究方向:中药民族药的鉴定.
通讯作者:万定荣(1958-),男(汉族),湖北荆门人,中南民族大学药学院教授,研究方向:植物药与民族药的资源、品质与应用研究,邮箱:wandr666@163.com.