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急性脑梗死患者血小板参数和纤维蛋白原、D-二聚体的变化及意义 被引量:2

The Changes and Significance of Four Platelet Parameters and Plasma Fibrinogen and D-dlmer in Patients with Acute Cerebral Infarction
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摘要 目的观察急性脑梗死患者4项血小板参数(PLT、MPV、PDW和P-LCR)和纤维蛋白原,D-二聚体的变化及意义。方法血小板4项参数采用SYSMEX全自动血液分析仪测定;血浆纤维蛋白原、D-二聚体水平分别采用Clauss法及乳胶免疫比浊法测定。结果急性脑梗死组的MPV、PDW和P-LCR均明显高于对照组,而PLT明显低于对照组,两组比较差异有统计学意义(P<0.05)。急性脑梗死组血浆纤维蛋白原与D-二聚体水平明显高于对照组,两组比较差异有统计学意义(P<0.05)。结论血小板4项参数以及血浆纤维蛋白原和D-二聚体水平的变化,对急性脑梗死患者的诊断具有重要意义。 OBJECTIVE To observe the changes and D-dlmer in patients with acute cerebral infarction. METHOD Platelet parameters (PLT,MPV,PDW and P-LCR) were detected with SYSMEX completely-automatic blood analyzer The levels of plasma flbrinogen and D- dlmer in 96 cases of acute cerebral infarction and 30 healthy people were detected with Clauss method and immunoturbidimetry method, respectively. RESULTS Compared with controlgroup, acute cerebral infarction group had significantly higher levels of MPV, PDW and P-LCR (P0.05); lower levels of PLT (P0.05) .The levels of plasma flbrinogen and D-dlmer in acute cerebral infarction group were significantly higher than those in control group (P0.05). CONCLUSION The four platelet parameters (PLT、 MPV、 PDW and P-LCR) and plasma flbrinogen and D-dlmer are useful for the diagnosis of acute cerebral infarction.
作者 陈科奇
机构地区 奉化市人民医院
出处 《中国初级卫生保健》 2010年第3期95-96,共2页 Chinese Primary Health Care
关键词 急性脑梗死 血小板参数 纤维蛋白原 D-二聚体 acute cerebral infarction platelet parameters flbrinogen D-dlmer
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  • 1尹长林,高宗良,司力.急性脑梗死患者血浆D-二聚体与纤维蛋白原的变化[J].中国临床保健杂志,2004,7(5):349-350. 被引量:15
  • 2杨颉,杨颖,赵春亭,王璐,陈兵,张锐.脑梗死患者血浆抗凝血酶及D-二聚体变化的临床意义[J].山东医药,2004,44(22):30-31. 被引量:7
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33091
  • 4李文惠.1995年中华神经科学会全国第四届脑血管会议通过各类脑血管病诊断要点[J].中华神经精神科杂志,1996,12(1):29-29.
  • 5Spada RS, Toscano G, Chiarenza S, et al. Ischemic stroke and fibrinogen in the elderly [ J ]. Arch C, erotuol Geriatr Suppl, 2004, 89(9 ) : 403-406.
  • 6Mary C, Aaron RF, Lu W, et al. Fibrin fragment D-dimer and the risk of future venous thrombosisE [ J]. Blood, 2003, 101:1 243-248.
  • 7Mark B, Peter L, Arm R, et al. Hemostatic function and progressing ischemic stroke D-dimer predicts early clinical progression [ J ]. Stroke, 2004, 35:1 421-425.
  • 8[5]Savage S, Saidivar E, Ruggeri ZM. Initiation of platelet adhension by arrest onto fibrinogen or translocation on von Willebrand factor [J].Cell, 1996,84:289 ~ 297.
  • 9谭其贤,张树平.临床血液学和血液学检验.北京:人民卫生出版社,2003.330-331.
  • 10Thompson CB, Eaton KA, Princiotta SM, et al. Size-dependent platelet subpopolstions: relationship of platelet volume to ultrastmcture, enzymatic activity, and function. BrJHaematology,1982,50 (3): 509-519.

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