摘要
目的观察斑蝥酸钠体外对人食管癌Eca109细胞凋亡的影响。方法应用MTT法,流式细胞仪检测,分析斑蝥酸钠对人食管癌Eca109细胞的生长和凋亡的影响。结果斑蝥酸钠作用24h可使人食管癌Eca109细胞生长明显抑制(P<0.01),并出现典型的凋亡峰。结论斑蝥酸钠对人食管癌Eca109细胞生长有抑制作用,可诱导食管癌细胞凋亡。
Objective To study sodium cantharidinate induced apoptosis of human esophageal carcinoma Eca109 in vitro. Methods The change of human esophageal carcinoma Eca109 treated with sodium cantharidinate were analyzed by MTT and FCM assay. Results Human esophageal carcinoma Eca109 were treated with sodium cantharidinate for 24 h, the cell proliferation was obviously inhibited （P〈0.01） and the ceils showed a typical apoptotic peak. Conclusion Sodium cantharidinate can inhibit ceil proliferation and induce ceil apoptosis of esophageal carcinoma ceils Eca109.
出处
《中国中医药信息杂志》
CAS
CSCD
2007年第3期22-23,共2页
Chinese Journal of Information on Traditional Chinese Medicine
基金
江苏省重点实验室开放基金资助
关键词
斑蝥酸钠
食管癌
生长抑制
细胞凋亡
实验研究
Sodium cantharidinate, esophageal carcinoma
growth inhibition
apoptosis
Experimental Study
