摘要
目的 :了解和分析武汉地区抗高血压药用药特点。方法 :以武汉地区 2 5家医院报告“长江流域医院信息网”2 0 0 0～ 2 0 0 2年数据 ,分年度按类别统计用药金额、比例、年增长率、金额排序及构成 ,并对重要药品进行分析。结果 :用药金额逐年相对下降。钙拮抗药 ,ACEI用药金额 3年分别排序第 1、第 2 ,两者金额之和占抗高血压药总金额 75 %以上 ,β 受体阻断药金额以每年 19%增幅上升 ,沙坦类金额每年分别以37.5 6 %、6 9.6 3%增幅增长。钙拮抗药以二氢吡啶类为主。抗高血压药构成比 ,合资药 >进口药 >国产药。结论 :抗高血压药药价下降与武汉地区对心血管系统药集中招标采购有关 ,钙拮抗药、ACEI、沙坦类、β 受体阻断药是主要用药 ,其中缓、控释制剂 ,对脂、糖代谢影响小 ,起效平缓 ,效果稳定 ,对心脏、肾脏有保护作用 ,不良反应小的品种最受临床、患者欢迎。研发国产品种应引起政府和企业足够重视。
Objective: To understand and analyze the characteristics of medication of antihypertensive agents in the area of Wuhan. Methods: Based on the data during 2000～2002 from the Analysis System of Drug-use in the Yangtze River Valley, money sum, proportion, rate of growth, sum arrangement and medication of drugs were investigated. Result: The money sum for drugs relatively decreased year by year. The first order of money sum was calcium antagonists, and the second, ACE inhibitors in the 3 years.The sum total of both was above 75%. The money sum of β-receptor antagonists rose by 19% each year and that of angiotensin Ⅱreceptor antagonists rose by 37.6% in 2001 and 69.6% in 2000. In calcium antagonists, dihydrodipines were the main drugs. The constituent proportion .of antihypertensive is joint ventures drug >imported drug>national drug. Conclusion: The decline of the money sum of antihypertensive is related to inviting tenders of drugs of the circulation system in the area of Wuhan calcium antagonists. AngiotensinⅡantagonists and β-receptor antagonists are the main drugs. Among them the slow release preparation and controllable release preparation, and the drugs which seldom affect fat and sugar metabolism but are able to protect heart and kidney and have little ADR are loved by clinical doctors and patients. Some attention must be fully paid to study and development of national drugs by the government and businesses.
出处
《药物流行病学杂志》
CAS
2003年第5期245-247,共3页
Chinese Journal of Pharmacoepidemiology
