摘要
目的分析良性前列腺增生(BPH)患者手术后血液高凝状态的影响因素,为预防BPH术后血栓形成提供参考。方法回顾性分析2022年4月—2023年9月于西安交通大学第一附属医院泌尿外科接受手术治疗的307例BPH患者的临床资料。依据术后凝血相关指标是否异常将患者分为高凝状态组和非高凝状态组。采用单因素及二元logistic回归分析筛选影响BPH患者术后血液高凝状态的危险因素。结果307例BPH患者中有45例(14.66%)术后出现血液高凝状态。单因素分析结果显示,高凝状态组与非高凝状态组间患者的年龄、住院时间、身体质量指数(BMI)、高血压史、糖尿病史及血型比较,差异均有统计学意义(P<0.05)。二元logistic回归分析结果显示,BMI(OR=1.135,95%CI:1.006~1.281,P=0.039)、高血压病史(OR=2.342,95%CI:1.103~4.927,P=0.027)、血型(OR=2.270,95%CI:1.066~4.836,P=0.034)是BPH术后血液高凝状态发生的独立危险因素。结论血型(非O型)、高BMI、高血压病史是BPH术后血液高凝状态发生的独立危险因素。
Objective To analyze the factors influencing hypercoagulable state in patients with benign prostatic hyperplasia(BPH)after surgery,so as to provide reference for preventing postoperative thrombosis in BPH.Methods A retrospective analysis was conducted on the clinical data of 307 BPH patients who underwent surgery in the Department of Urology at the First Affiliated Hospital of Xi‘an Jiaotong University during Apr.2022 and Sep.2023.Patients were divided into the hypercoagulable state group and non-hypercoagulable state group based on the presence of abnormal postoperative coagulation parameters.Single factor and binary logistic regression analysis were used to screen risk factors affecting postoperative blood hypercoagulability in BPH patients.Results Among the 307 BPH patients,45(14.66%)developed a hypercoagulable state postoperatively.Univariate analysis revealed statistically significant differences between the hypercoagulable and non-hypercoagulable groups regarding patients‘age,length of hospital stay,body mass index(BMI),history of hypertension,history of diabetes,and blood type(P<0.05).Binary logistic regression analysis identified BMI(OR=1.135,95%CI:1.006-1.281,P=0.039),history of hypertension(OR=2.342,95%CI:1.103-4.927,P=0.027),and blood type(OR=2.270,95%CI:1.066-4.836,P=0.034)as independent risk factors for postoperative hypercoagulable state.Conclusion Non-O blood type,high BMI,and history of hypertension are independent risk factors for the occurrence of hypercoagulable state following surgery for BPH.
作者
万泉
邵聪
刘哲
文永安
杨林
WAN Quan;SHAO Cong;LIU Zhe;WEN Yongan;YANG Lin(Department of Urology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710001;Department of Urology,Affiliated Hospital of Xizang Minzu University,Xianyang 712000;Hebi Institute of Engineering and Technology,Henan Polytechnic University,Hebi 458000,China)
出处
《现代泌尿外科杂志》
2025年第8期680-684,共5页
Journal of Modern Urology
关键词
良性前列腺增生
血液高凝状态
下尿路症状
benign prostatic hyperplasia
hypercoagulable state
lower urinary tract symptoms
作者简介
通信作者:杨林,主任医师。E-mail:forest3011@126.com;通信作者:文永安,主任医师。E-mail:wenyongan1972@163.com;万泉,硕士研究生在读,住院医师。研究方向:泌尿外科。E-mail:spring_0526@163.com。
