摘要
目的:挖掘魏伟教授治疗中心性浆液性脉络膜视网膜病变(Central Serous Chorioretinopathy,CSC)的用药规律,分析魏伟教授从脏腑辨治CSC的思路,进一步总结魏伟教授治疗CSC的经验。方法:收集魏伟教授临床治疗CSC的中药处方并建立数据库,利用SPSS、 Excel对所用中药按功效、四气、五味、归经进行统计,对30味高频中药进行聚类分析,挖掘用药规律。结果:共收集处方379张,涉及中药128味。按中药功效统计,使用最多的是利水渗湿药;按中药四气、五味统计,使用最多的是寒性药和甘味药;按中药归经统计,使用味数最多的为入肝经药,使用频数最多的为入肺经药。通过聚类分析获得茯苓–泽泻、白术–猪苓、甘草–滑石、冬瓜子–玉米须等共8组常用药对,以及茯苓–泽泻–白术–猪苓–甘草–滑石、冬瓜子–玉米须–当归–车前子–柴胡–夏枯草等共4组常用药组。结论:魏伟教授认为,CSC的发病多与脾、肝、肾三脏相关,经用药规律分析及临床学习总结可得出魏伟教授从脏腑辨治CSC的三条经验:健脾利水举足轻重、从肝而治贯穿始终、补肾滋阴明目点睛。
Objective:To explore the medication rule of Professor WEI Wei in the treatment of central serous chorioretinopathy(CSC),so as to analyze the thinking of treating CSC from Zang-fu organs(脏腑)differentiation by Professor WEI Wei,and further summarize the experience of Professor WEI Wei in treating CSC.Methods:The TCM prescriptions for treating CSC of Professor WEI Wei were collected and the relevant databases were established.SPSS and Excel were used to statistically analyze clinical efficacy,medicinal properties,medicinal flavors,and meridian tropism of all Chinese medicines in the included prescriptions,and cluster analysis on 30 high-frequency Chinese medicines was performed to mine the medication rule.Results:A total of 379 prescriptions were collected,involving 128 Chinese medicines.According to the efficacy statistics of Chinese medicines included,the most commonly used medicines were clearing dampness medicines.According to the statistics of medicinal properties and medicinal flavors,the most commonly used medicines were cold property medicines and sweet medicines.According to the statistics of meridian tropism of Chinese medicines,the medicine with the highest species was liver meridian-absorbed medicine,and the medicine with the highest frequency was lung meridian-absorbed medicine.Through cluster analysis,a total of 8 pairs of commonly used medicines were identified,including Fuling(Poria)-Zexie(Rhizoma Alismatis),Baizhu(Rhizoma Atractylodis Macrocephalae)-Zhuling(Polyporus),Gancao(Radix Glycyrrhizae)-Huashi(Talcum),Dongguazi(Semen Benincasae)-Yumixu(Corn Stigma),etc.,and 4 groups of commonly used medicine combinations such as Fuling-Zexie-Baizhu-Zhuling-Gancao-Huashi,and Dongguazi-Yumixu-Danggui(Radix Angelicae Sinensis)-Cheqianzi(Semen Plantaginis)-Chaihu(Radix Bupleuri)-Xiakucao(Spica Prunellae).Conclusion:Professor WEI Wei believes that the onset of CSC is mostly related to spleen,liver,and kidneys.By the analysis of medication rule and the summary of clinical study,Professor WEI Wei’s three clinical experiences in distinguishing and treating CSC from Zang-fu organs are drawn as follows:strengthening spleen and dredging water is important,treating the disease from the liver runs through the whole process,and the tonifying kidney and nourishing Yin(阴)method is used to brighten the eyes.
出处
《中医临床研究》
2025年第14期8-13,共6页
Clinical Journal Of Chinese Medicine
关键词
中心性浆液性脉络膜视网膜病变
脏腑
用药规律
经验
Central serous chorioretinopathy
Zang-fu organs
Medication rule
Clinical experience
