摘要
目的探究经颅磁刺激(TMS)联合感统训练对孤独症谱系障碍(ASD)患儿神经发育及睡眠功能的影响。方法选取2021年5月至2022年5月大连市妇女儿童医疗中心(集团)儿保门诊收治的80例ASD患儿作为研究对象,通过随机数字表法分为对照组与观察组,每组40例。对照组用TMS治疗仪刺激左侧背外侧前额叶皮质(DLPEC),每次治疗20 min,1次/d,每周连续治疗5 d;观察组在对照组基础上联合感觉统合训练进行治疗,感统训练30 min/次,1次/d,每周连续训练5 d。两组均持续治疗3个月。分别评定并对比两组患儿治疗前后ASD严重程度、发育商评分、行为评分,记录并对比两组患儿治疗后睡眠问题发生率。结果两组患儿治疗前儿童孤独症评定量表(CARS)评分、孤独症儿童行为量表(ABC)评分、发育商(DQ)评分比较,差异无统计学意义(P>0.05);两组患儿治疗后的CARS评分、ABC评分低于本组治疗前,DQ评分高于本组治疗前,差异有统计学意义(P<0.05);观察组患儿治疗后的CARS评分、ABC评分低于对照组,DQ评分高于对照组,睡眠问题少于对照组,差异有统计学意义(P<0.05)。结论TMS联合感统训练可有效减轻患儿ASD严重程度,改善患儿神经发育并提升其睡眠质量。
Objective To explore the effect of transcranial magnetic stimulation(TMS)combined sensory integration training on neurodevelopment and sleep function in children with autism spectrum disorder(ASD).Methods A total of 80 children with ASD admitted to the Children's Care Clinic of Dalian Women and Children's Medical Group from May 2021 to May 2022 were selected as research objects and divided into control group and observation group by random number table method,with 40 cases in each group.The left dorsolateral prefrontal cortex(DLPEC)was stimulated by TMS therapy instrument in the control group,with each treatment for 20 min,once a day,and continuous treatment for 5 days a week.The observation group was combined with sensory integration training on the basis of control group,sensory integration training 30 min/time,once a day,continuous training for 5 days a week.Both groups were treated for three months.ASD severity,developmental quotient score and behavioral score were evaluated and compared between the two groups before and after treatment,and the incidence of sleep problems was recorded and compared between the two groups.Results There were no significant differences in the scores of children with children autism rating scale(CARS),autism behavior checklist(ABC)and developmental quotient(DQ)between the two groups before treatment(P>0.05).The CARS score and ABC score of the two groups after treatment were lower than those before treatment,and the DQ scores of the two groups were higher than those before treatment,with statistically significant differences(P<0.05).After treatment,CARS score and ABC score in observation group were lower than those in control group,DQ scores were higher than those in control group,and sleep problems were less than those in control group,with statistically significant differences(P<0.05).Conclusion TMS combined sensory integration training can effectively reduce the severity of ASD,improve the neurodevelopment and improve the sleep quality of children.
作者
孙显婷
SUN Xianting(Children's Care Clinic,Dalian Women and Children's Medical Group,Liaoning Province,Dalian116000,China)
出处
《中国当代医药》
CAS
2024年第5期111-115,共5页
China Modern Medicine
关键词
经颅磁刺激
感觉统合训练
孤独症谱系障碍
神经发育
睡眠功能
Transcranial magnetic stimulation
Sensory integration training
Autism spectrum disorder
Neurodevelopment
Sleep function
作者简介
孙显婷(1986-),女,吉林人,汉族,硕士,研究方向:儿童保健、孤独症谱系障碍、注意缺陷多动障碍和抽动障碍。
