摘要
目的分析郑州地区10664例过敏性疾病患者常见过敏原的流行特征。方法选取2013年1月至2021年8月在本院就诊且进行血清过敏原筛查的患者10664例,对其血清过敏原sIgE检测结果进行回顾性分析。结果10664例患者的过敏原sIgE总阳性率为69.82%。吸入性过敏原sIgE阳性率高于食物性(χ^(2)=99.15,P<0.01)。吸入性过敏原sIgE构成比前3位分别为草树组合、尘螨组合、蟑螂;食物性过敏原sIgE构成比前3位分别为鸡蛋白、牛奶、海鲜组合。男性患者食物性过敏原sIgE阳性率高于女性(χ^(2)=8.18,P<0.01)。幼儿期食物性过敏原sIgE阳性率最高(χ^(2)=125.92,P<0.05);学龄组、学龄前组吸入性过敏原sIgE阳性率最高(χ^(2)=283.76,P<0.01)。蟑螂、屋尘sIgE占比呈逐年下降趋势,牛奶、花生、羊肉及海鲜组合sIgE占比逐年上升。结论郑州地区吸入性及食物性过敏原sIgE抗体阳性率构成比前3位分别为草树组合、尘螨、蟑螂及鸡蛋白、牛奶、海鲜组合。近年来需注意牛奶、花生、羊肉及海鲜过敏的情况。
Objective To invesitgate the epidemiological characteristics of common allergens in 10664 patients with allergic diseases in Zhengzhou area.Methods A total of 10664 patients visited our hospital and underwent serum allergen screening during January 2013 and August 2021 were selected,and their serum sIgE results were retrospectively analyzed.Results The total positive rate of sIgE to allergens in 10664 patients was 69.82%.The positive rate of sIgE to inhalant allergens was significantly higher than that to ingestive allergens(χ^(2)=99.15,P<0.01).The top three inhalant allergens were grass and tree combination,dust mite combination,and cockroach.The top three ingestive allergens were egg protein,milk,and seafood combination.The positive rate of sIgE to ingestive allergens in males was significantly higher than that in females(χ^(2)=8.18,P<0.01).The highest positive rate of sIgE to ingestive allergens was found in the early childhood period(χ^(2)=125.92,P<0.05).The highest positive rate of sIgE to inhalant allergens was found in the school-age and preschool periods(χ^(2)=283.76,P<0.01).The proportions of sIgE to cockroach and house dust mite showed a decreasing trend year by year,while the proportions of sIgE to milk,peanut,lamb,and seafood combination showed an increasing trend year by year.Conclusion The top three inhalant and ingestive allergens in Zhengzhou area are grass and tree combination,dust mite,cockroach and egg protein,milk,seafood combination,respectively.In recent years,the allergies to milk,peanut,lamb,and seafood should be paid attention.
作者
泰淑红
魏园玉
宋晓妍
王媛
牛超
王鹏
TAI Shuhong;WEI Yuanyu;SONG Xiaoyan;WANG Yuan;NIU Chao;WANG Peng(Department of Laboratory Medicine,the Third Affiliated Hospital of Zhengzhou University/Henan Maternity and Child Health Hospital,Zhengzhou 450052,Henan,China)
出处
《临床检验杂志》
CAS
2024年第1期18-21,共4页
Chinese Journal of Clinical Laboratory Science
基金
河南省医学科技攻关计划联合共建项目(LHGJ20210471)。
关键词
过敏
过敏原
免疫球蛋白E
回顾性分析
allergy
allergen
immunoglobulin E
retrospective analysis
作者简介
泰淑红,1982年生,女,副主任技师,硕士,从事临床检验诊断学工作;通信作者:王鹏,副主任技师,硕士,E-mail:wpplew@163.com。
