摘要
目的分析2020年青岛市成年居民的血脂异常流行现状,为血脂异常的精准防控提供科学依据。方法于2019年5月—2020年9月采用多阶段分层随机抽样方法,抽取6240名青岛市≥18岁常住居民为调查对象。抽取调查对象静脉血,检测总胆固醇(total cholesterol,TC)、三酰甘油(triglyceride,TG)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)和低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)。数据经复杂加权调整后,分析不同人群特征的血脂总异常率、高TC血症、高TG血症、高LDL-C血症和低HDL-C血症患病率的情况。结果本研究最终纳入分析6040人。经复杂加权计算后,2020年青岛市成年居民血脂总异常患病率为40.53%(95%CI:39.26%~41.74%),其中男性[46.38%(95%CI:44.62%~48.18%)]高于女性[34.55%(95%CI:32.91%~36.29%)],差异有统计学意义(χ^(2)=121.918,P<0.01)。成年居民高TC血症患病率为13.48%(95%CI:12.64%~14.36%)、高TG血症患病率为20.78%(95%CI:19.78%~21.82%)、高LDL-C血症患病率为7.96%(95%CI:7.32%~8.68%)、低HDL-C血症患病率为14.81%(95%CI:13.90%~15.70%),其中高TG血症患病率和低HDL-C血症患病率均为男性高于女性(P<0.01),而高TC血症患病率为女性高于男性(P<0.01)。结论青岛市成年人血脂异常患病率较高,男性高于女性,高TG血症和低HDL-C血症是该地区血脂异常的主要形式。
Objective To investigate the dyslipidemia prevalence among adults≥18 years in Qingdao,so as to provide references precision prevention and control of this condition.Methods From May 2019 to September 2020,6240 residents of 18 years and above in Qingdao were selected using multi-stage stratified random sampling.Venous blood samples were collected from the participants for measurement of levels of total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C)and low-density lipoprotein cholesterol(LDL-C)..The prevalence of dyslipidemia,hypercholesterolemia,hypertriglyceridemia,high LDL-C,and low HDL-C of different groups by selected demographic characteristics was analyzed incorporating complex survey weights.Results A total of 6040 valid samples were included.After weighting,the dyslipidemia prevalence among adults in Qingdao was 40.53%(95%CI:39.26%-41.74%),statistically significantly higher in males(46.38%,95%CI:44.62%-48.18%)than in females(34.55%,95%CI:32.91%-36.29%)(χ^(2)=121.918,P<0.01).The prevalence of hypercholesterolemia,hypertriglyceridemia,high blood LDL-C and low blood HDL-C was 13.48%(95%CI:12.64%-14.36%),20.78%(95%CI:19.78%-21.82%),7.96%(95%CI:7.32%-8.68%),14.81%(95%CI:13.90%-15.70%),respectively.The prevalence rates of hypertriglyceridemia and low HDL-C were higher in males than in females(P<0.01),while that of hypercholesterolemia was higher in females than in males(P<0.01).Conclusions The prevalence of dyslipidemia in adult residents of Qingdao is high and the rate in males is even higher than in females.Hypertriglyceridemia and low blood HDL-C are two major types of dyslipidemia in this area.
作者
赵园园
薛晓嘉
陶然
房盛夏
郑晓艳
张华
汪韶洁
段海平
ZHAO Yuanyuan;XUE Xiaojia;TAO Ran;FANG Shengxia;ZHENG Xiaoyan;ZHANG Hua;WANG Shaojie;DUAN Haiping(Qingdao Municipal Center for Disease Control and Prevention/Qingdao Institute of Preventive Medicine,Qingdao,Shandong 266033,China;不详)
出处
《中国预防医学杂志》
CAS
CSCD
北大核心
2023年第9期979-985,共7页
Chinese Preventive Medicine
基金
青岛市医疗卫生重点学科建设项目(2020A09)
青岛市医药科研指导计划(2019-WJZD149)。
关键词
血脂异常
患病率
横断面研究
成年人
Dyslipidemias
Prevalence
Cross-sectional studies
Adult
作者简介
赵园园,博士研究生,主管技师,主要从事慢性病防制研究;通信作者:段海平,E-mail:duan_hp@126.com。