摘要
肉芽肿性乳腺炎(GM)是一种临床少见的良性乳腺炎症性疾病,近年来,发病率逐年攀升,但到目前为止,其病因及发病机制尚不明确。该病主要好发于有母乳喂养史的育龄期妇女,好发年龄为30~42岁。常以受累乳腺红肿、疼痛为主要临床表现,局部可扪及肿块,病程较长。以组织病理学诊断作为“金标准”,活检结果显示肉芽肿形成,并伴有多核巨细胞、上皮样组织细胞和浆细胞浸润。目前,对GM的治疗方案包括药物治疗(抗菌药物、类固醇激素、免疫抑制剂)、手术治疗、中医药治疗及多种治疗方式联合应用等,但尚未形成统一的诊疗规范。该文主要对GM常见病因及发病机制、临床诊疗最新进展进行综述。
Granulomatous mastitis(GM)is a rare benign mastitis disease in clinical practice.In recent years,the incidence has been increasing year by year,but so far,its etiology and pathogenesis are still unclear.This disease mainly occurs in women of childbearing age who have a history of breastfeeding,with prevalence old is 30-42 years.The main clinical manifestations are often affected breast redness,swelling,and pain,with local palpable masses and a longer course of disease.Using histopathological diagnosis as the“gold standard”,the biopsy results showed granuloma formation accompanied by multinucleated giant cells,epithelioid tissue cells,and plasma cell infiltration.At present,the treatment plans for GM include drug therapy(antibiotics,steroids,immunosuppressants),surgical treatment,traditional Chinese medicine treatment,and the combination of multiple treatment methods,but a unified diagnosis and treatment standard has not yet been formed.This article mainly provides a brief review of the common causes and pathogenesis of GM,as well as the latest progress in clinical diagnosis and treatment.
作者
崔天玥(综述)
张胜初(审校)
CUI Tianyue;ZHANG Shengchu(Department of Thyroid Breast Surgery,The First College of Clinical Medical Science of China Three Gorges University/Yichang Central People′s Hospital,Yichang,Hubei 443000,China)
出处
《现代医药卫生》
2023年第15期2640-2645,共6页
Journal of Modern Medicine & Health
关键词
肉芽肿性乳腺炎
发病机制
诊疗方案
综述
Granulomatous mastitis
Pathogenesis
Diagnosis and treatment plan
Review
作者简介
通信作者:张胜初,E-mail:xgzsc@126.com。
