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推拿疗法对项背肌筋膜炎伴焦虑患者血清5-HT及脑源性神经营养因子的影响 被引量:11

Effects of a massage therapy on the levels of serum 5-hydroxytryptamine and brain-derived neurotrophic factors in patients with dorsonuchal myofascitis and anxiety
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摘要 目的评价推拿疗法对项背肌筋膜炎伴焦虑患者疼痛、睡眠、情绪及血清5-羟色胺(5-HT)、脑源性神经营养因子(BDNF)的影响。方法将62例患者随机分为对照组和治疗组,各31例,对照组采用脉冲超短波电疗机配合微波治疗仪进行治疗,治疗组采用推拿疗法进行治疗,评定2组患者的视觉模拟评分(VAS)、焦虑自评量表(SAS)及阿森斯失眠量表(AIS)以及血清中5-HT、BDNF含量。结果治疗后,与对照组相比,治疗组患者的VAS、SAS、AIS评分明显下降(P<0.05);治疗组患者血清中5-HT含量较对照组显著降低(P<0.05);治疗组患者血清中BDNF含量明显高于对照组(P<0.05)。结论推拿疗法可以明显改善项背肌筋膜炎伴焦虑患者的疼痛、不良情绪及睡眠质量,可能与调节血清中5-HT及BDNF水平有关。 Objective To evaluate the effects of a massage therapy on pain,sleep,mood,serum 5-hydroxytryptamine(5-HT)and brain-derived neurotrophic factors(BDNF)in patients with dorsonuchal myofascitis and anxiety.Methods Sixty-two patients were randomly divided into a control group and a treatment group,with 31 patients in each group.The control group was treated with a pulse ultrashort wave electrotherapy machine combined with a microwave therapy instrument,while the treatment group was treated with a massage therapy.The scores of the Visual Analogue Scale(VAS)indexes,the Self-Rating Anxiety Scale(SAS)indexes,the Athens Insomnia Scale(AIS)indexes,and the contents of serum 5-HT and BDNF were assessed in both groups.Results After treatment,compared with the control group,the VAS,SAS,and AIS scores of the treatment group were significantly decreased(P<0.05);The serum 5-HT content in the treatment group was significantly lower than that in the control group(P<0.05);The serum BDNF content in the treatment group was significantly higher than that in the control group(P<0.05).Conclusion The massage therapy can significantly improve the pain,bad mood and sleep quality in patients with dorsonuchal myofascitis and anxiety,which may be related to its regulation of serum 5-HT and BDNF levels.
作者 郭皓泽 王宇峰 雷斯媛 宋柏林 GUO Haoze;WANG Yufeng;LeI Siyuan;SONG Bailin(Changchun University of Chinese Medicine,Changchun 130117,China)
机构地区 长春中医药大学
出处 《吉林中医药》 2023年第7期849-851,共3页 Jilin Journal of Chinese Medicine
基金 吉林省科技发展计划项目(YDZJ202201ZYTS184)。
关键词 项背肌筋膜炎 焦虑 五羟色胺 脑源性神经营养因子 dorsonuchal myofascitis anxiety 5-hydroxytryptamine brain-derived neurotrophic factor
作者简介 郭皓泽(1993-),女,博士研究生,主要从事经穴推拿治疗脏腑病的研究;通信作者:宋柏林,电子信箱-songbailin2022@126.com。
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