摘要
目的:了解川滇野丁香Leptodermis pilosa全株的化学成分。方法:采用硅胶、MCI、Sephadex LH-20等柱色谱对川滇野丁香全株的化学成分进行分离纯化,依据理化性质和现代波谱分析技术进行结构鉴定。结果:从川滇野丁香全株75%乙醇提取物乙酸乙酯萃取部位中分离得到8个化合物,分别鉴定为齐墩果酸(1)、2α-羟基齐墩果酸(2)、阿江榄仁素(3)、东莨菪内酯(4)、咖啡酸甲酯(5)、丁香酸(6)、水杨酸(7)、胡萝卜苷(8)。结论:所有化合物均为首次从该植物中分离得到,其中化合物2~7为首次从野丁香属植物中分离得到。
Objective:To study the chemical constituents of the whole-plant of Leptodermis pilosa.Methods:Silica gel,MCI,and Sephadex LH-20 column chromatography were used to isolate and purify the chemical constituents of L.pilosa.The structures were identified based on physicochemical properties and modern spectroscopic analysis techniques.Results:Eight compounds were isolated from the ethyl acetate fraction of the 75%ethanol extract of the whole-plant of L.pilosa and identified as oleanolic acid(1),2α-hydroxyloleanolic acid(2),arjungenin(3),scopoletin(4),methyl caffeate(5),syringic acid(6),salicylic acid(7),and daucosterol(8).Conclusion:All the compounds were isolated from L.pilosa for the first time,and compounds 2-7 were first isolated from genus Leptodermis.
作者
史凯旋
李靖
凌浩威
刘蓉
肖朝江
姜北
Shi Kaixuan;Li Jing;Ling Haowei;Liu Rong;Xiao Chaojiang;Jiang Bei(Yunnan Key Laboratory of Screening and Research on Anti-Pathogenic Plant Resources from Western Yunnan,Dali,Yunnan 671000,China;College of Pharmacy,Dali University,Dali,Yunnan 671000,China)
出处
《大理大学学报》
2023年第8期11-14,共4页
Journal of Dali University
基金
国家自然科学基金项目(81960637)
云南省滇西抗病原植物资源筛选研究重点实验室项目(202105AG070003)。
关键词
川滇野丁香
化学成分
酚类
三萜
Leptodermis pilosa
chemical constituents
phenols
triterpenoids
作者简介
第一作者:史凯旋,硕士研究生,主要从事天然产物研究;通信作者:姜北,教授,博士,E-mail:jiangbei@dali.edu.cn。
