摘要
目的:探讨个体化经颅磁刺激方案对孤独症合并睡眠障碍患儿的干预效果。方法:选取90例孤独症合并睡眠障碍患儿,随机分为对照组与观察组各45例。2组均接受常规康复治疗,对照组在常规治疗的基础上实施常规重复经颅磁刺激(rTMS)治疗,观察组依据患儿的事件相关电位(ERP)的检查结果进行个体化rTMS治疗;采用儿童孤独症评定量表(CARS)、孤独症治疗评估表(ATEC)、儿童睡眠习惯调查问卷(CSHQ)以及家庭睡眠习惯调查表(FISH)比较2组的干预效果。结果:与治疗前相比,2组患儿治疗后CARS、ATEC评分均显著降低(均P<0.05),且观察组的CARS、ATEC评分均显著低于对照组(均P<0.05);与治疗前相比,2组患儿治疗后CSHQ评分显著降低(均P<0.05),FISH评分显著增加(均P<0.05),且观察组的CSHQ评分显著低于对照组(P<0.05),FISH评分显著高于对照组(P<0.05)。结论:根据ERP结果进行个体化rTMS治疗方案对ASD合并睡眠障碍患儿的干预效果优于常规rTMS治疗。
Objective:To investigate the intervention effect of individualized transcranial magnetic stimulation(TMS)on children with autism complicated with sleep disorder.Methods:A total of 90 children with autism complicated with sleep disorder were randomly divided into control group(n=45)and observation group(n=45)by a random number table method.Both groups received routine rehabilitation treatment.The control group was treated with routine repeated transcranial magnetic stimulation(rTMS)on the basis of routine treatment,and the observation group was treated with individualized rTMS according to the results of event-related potential(ERP).Children’s Autism Rating Scale(CARS),Autism Treatment Evaluation Scale(ATEC),Children’s Sleep Habits Questionnaire(CSHQ)and Family Sleep Habits Questionnaire(FISH)were used to compare and analyze the intervention effect between the two groups.Results:Compared with those before the treatment,the autism-related CARS and ATEC scores in two groups after treatment were significantly decreased(P<0.05),and the CARS and ATEC scores in the observation group were significantly lower than those in the control group(P<0.05).Compared with those before treatment,the sleep-related CSHQ scores in the two groups after treatment were significantly decreased(P<0.05),and the FISH scores were significantly increased(P<0.05),and the CSHQ scores in the observation group were significantly lower than those in the control group(P<0.05),and the FISH scores in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:The intervention effect of individualized rTMS treatment plan based on ERP results in children with autism complicated with sleep disturbance is better than that of conventional rTMS treatment.
作者
徐翠香
孙昊
沈文宾
周婉琼
胡玉芳
李恩耀
Xu Cuixiang;Sun Hao;Shen Wenbin(Department of Pediatric Rehabilitation Medicine,the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450003,China)
出处
《中国康复》
2023年第4期195-199,共5页
Chinese Journal of Rehabilitation
基金
河南省自然科学基金(212300410399)。
关键词
颅磁刺激
孤独症
睡眠障碍
干预效果
事件相关电位
transcranial magnetic stimulation
autism
sleep disturbance
intervention effect
event-related potential
作者简介
徐翠香(1985-),女,主治医师,主要从事儿童孤独症的诊断与治疗方面的研究;通讯作者:李恩耀,Lienyao2016@163.com。
