摘要
目的探讨^(18)F-FDG PET/CT、超声造影及联合应用对胰腺病变良恶性鉴别的诊断价值。方法回顾性分析2015年1月—2020年12月于唐山市工人医院行^(18)F-FDG PET/CT和超声造影检查的胰腺病变患者资料,以病理结果为标准,分析^(18)F-FDG PET/CT、超声造影及两者联合时对胰腺病变良恶性鉴别诊断的灵敏度、特异度、准确度、阳性预测值及阴性预测值。计量资料组间比较采用t检验;计数资料组间比较采用χ2检验。结果108例病变中恶性83例、良性25例,^(18)F-FDG PET/CT诊断灵敏度、特异度、准确度、阳性预测值及阴性预测值分别为86.75%、80.00%、85.19%、93.51%及64.52%,超声造影分别为69.88%、7600%、71.30%、90.63%及43.18%,两者联合应用时分别为90.36%、84.00%、88.89%、94.94%及72.41%。^(18)F-FDG PET/CT与超声造影两者间灵敏度、准确度比较差异均有统计学意义(P值均<0.05)。结论^(18)F-FDG PET/CT对胰腺病变良恶性鉴别具有较高的诊断价值,高于超声造影,两者联合应用时可进一步提高诊断价值。
Objective To assess the value of ^(18)F-FDG PET/CT,contrast-enhanced ultrasound,and their combination in the differential diagnosis of benign and malignant pancreatic lesions.Methods A retrospective analysis was performed on patients with pancreatic lesions who underwent ^(18)F-FDG PET/CT and contrast-enhanced ultrasound who were admitted to Tangshan Gongren Hospital from January 2015 to December 2020.The imaging results were confirmed by pathology examination to evaluate diagnostic sensitivity,specificity,accuracy,positive and negative predictive value.The t-test was used for comparison of continuous data between two groups,and the chi-square test was used for comparison of categorical data between groups.Results There were 83 malignant lesions and 25 benign lesions in 108 patients.The sensitivity,specificity,accuracy,positive and negative predictive value were 86.75%,80.00%,85.19%,93.51%and 6452%for ^(18)F-FDG PET/CT;and 69.88%,76.00%,71.30%,90.63%and 43.18%for contrast-enhanced ultrasound,respectively.The two methods differed significantly in sensitivity and accuracy(all P<0.05),but not in specificity,negative and positive predictive value(all P>0.05).When combined with the contrast-enhanced ultrasound,^(18)F-FDG PET/CT had an increased sensitivity,specificity,accuracy,positive and negative predictive value of 90.36%,84.00%,88.89%,94.94%and 72.41%,respectively,though this was not statistically significant due to the increased signal of blood supply in the lesions.Conclusion ^(18)F-FDG PET/CT has a better performance than contrast-enhanced ultrasound in the differential diagnosis of benign and malignant pancreatic lesions,and their combination can improve the diagnostic value.
作者
郑立春
张晓明
余天颖
李洁
邓小倩
欧阳向柳
ZHENG Lichun;ZHANG Xiaoming;YU Tianying;LI Jie;DENG Xiaoqian;OUYANG Xiangliu(Department of Nuclear Medicine,Tangshan Gongren Hospital,Tangshan,Hebei,063000,China;Department of Gynaecology and Obstetrics,Tangshan Gongren Hospital,Tangshan,Hebei,063000,China;Department of Ultrasound,Tangshan Gongren Hospital,Tangshan,Hebei,063000,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2022年第12期2774-2779,共6页
Journal of Clinical Hepatology
基金
唐山市科学技术研究与发展计划(19150220E)。
作者简介
通信作者:欧阳向柳,usouyangxl@163.com。
