摘要
目的分析2012—2020年宁波市结核分枝杆菌和艾滋病病毒(MTB/HIV)双重感染筛查结果,为完善结核病防控策略提供参考。方法通过2012-2020年《宁波市结核菌/艾滋病病毒双重感染防治管理工作年度报表》收集结核病病例接受HIV检测、艾滋病病毒感染者和艾滋病患者(HIV/AIDS)接受MTB检查、MTB/HIV双重感染病例治疗及转归资料,分析MTB/HIV双重感染的筛查和治疗转归情况。结果2012-2020年宁波市新报告结核病病例35385例,接受HIV筛查5854例,年均筛查率为17.57%,2012-2020年HIV筛查率呈上升趋势(χ^(2)_(趋势)=4926.309,P<0.001);检出HIV阳性11例,年均阳性率为0.19%。接受MTB筛查HIV/AIDS病例26043例,年均筛查率为95.78%,2012-2020年MTB筛查率呈上升趋势(χ^(2)_(趋势)=79.077,P<0.001);检出结核病81例,年均检出率为0.31%。MTB/HIV双重感染病例92例,同时接受抗结核和抗病毒治疗81例,占88.04%;单纯抗结核治疗8例,占8.70%;单纯抗病毒治疗2例,占2.17%;未治疗1例,占1.09%。89例接受抗结核治疗的MTB/HIV双重感染病例中,治愈27例,占30.34%;完成疗程53例,占59.55%;死亡7例。结论2012—2020年宁波市HIV/AIDS病例MTB筛查率和MTB/HIV双重感染病例抗结核治疗成功率较高,但结核病病例HIV筛查率需进一步提升。
Objective To analyze the screening results of Mycobacterium tuberculosis(MTB)and HIV co-infections in Ningbo City from 2012 to 2020,so as to provide insights into improving the tuberculosis control strategy.Methods Data pertaining to HIV antibody testing among tuberculosis patients,MTB testing among HIV/AIDS patients,treatment of patients with MTB and HIV co-infections and prognosis of anti-tuberculosis therapy were collected from the annual working reports for the management of MTB and HIV co-infections in Ningbo City from 2012 to 2020,and the screening,treatment and prognosis of MTB and HIV co-infections were analyzed.Results A total of 35385 newly identified tuberculosis patients were reported in Ningbo City from 2012 to 2020,and there were 5854 cases receiving HIV testing.The annual mean percentage of HIV screening was 17.57%,and the HIV screening rate appeared a tendency towards a rise in Ningbo City from 2012 to 2020(χ^(2)_(trend)=4926.309,P<0.001).Eleven patients were tested positive for HIV,with an annual mean HIV positive rate of 0.19%.A total of 26043 HIV/AIDS patients received MTB screening,with an annual mean screening rate of 95.78%,and the annual screening rate of MTB appeared a tendency towards a rise in Ningbo City from 2012 to 2020(χ^(2)_(trend)=79.077,P<0.001).A total of 81 tuberculosis patients were detected,with an annual mean detection rate of 0.31%.Among the 92 patients with MTB and HIV co-infections,there were 81 patients receiving anti-tuberculosis and antiviral therapy simultaneously(88.04%),8 cases receiving anti-tuberculosis therapy alone(8.70%),2 cases receiving antiviral therapy alone(2.17%)and 1 case without therapy(1.09%).Among the 89 MTB and HIV co-infected patients receiving anti-tuberculosis therapy,27 cases were cured(30.34%),53 cases completing the course of treatment(59.55%)and 7 cases died.Conclusions The MTB screening rate among HIV/AIDS patients and the percentage of MTB and HIV co-infected patients with successful anti-tuberculosis treatment were high in Ningbo City from 2012 to 2020;however,the HIV screening rate should be improved among tuberculosis patients.
作者
桑国鑫
陈同
车洋
陈云鹏
贺天锋
SANG Guoxin;CHEN Tong;CHE Yang;CHEN Yunpeng;HE Tianfeng(Department of Tuberculosis Control and Prevention,Ningbo Center for Disease Control and Prevention,Ningbo,Zhejiang 315010,China;School of Medicine,Ningbo University,Ningbo,Zhejiang 315211,China)
出处
《预防医学》
2022年第11期1121-1124,共4页
CHINA PREVENTIVE MEDICINE JOURNAL
基金
浙江省医药卫生科技项目(2022KY1189)
浙江省医药卫生科技项目(2021KY334)
浙江省公益基金项目(LGF22H260003)
浙江省医学重点学科项目(07–013)
宁波市卫生品牌学科基金(PPXK2018-10)
关键词
结核病
艾滋病
双重感染
筛查
tuberculosis
AIDS
co-infection
screening
作者简介
桑国鑫,硕士,初级检验技师,主要从事疾病预防与控制工作;通信作者:贺天锋,E-mail:hetfnbcdc@163.com。
