摘要
目的:分析重庆市万州区结核菌/艾滋病病毒(TB/HIV)双重感染患者治疗信息,为进一步完善该区TB/HIV双重感染防控策略提供参考依据。方法:采用描述性流行病学方法对2015—2020年万州区TB/HIV双向筛查资料进行分析。结果:2015—2020年重庆市万州区新登记结核病患者6 391例,接受HIV抗体检测4 494例,HIV抗体检测率70.75%,检出HIV阳性17例,HIV阳性检出率0.38%。新检出艾滋病患者中开展结核病检查850例,结核病检查率92.79%(850/916),发现46例结核病患者,患者检出率5.41%。既往可随访的HIV/AIDS患者中开展结核病检查3 862例次,结核病检查率91.49%(3 862/4 221),发现患者37例,患者检出率0.96%。新检出艾滋病患者中结核病检出率(5.41%)高于既往可随访到的HIV/AIDS患者中结核病检出率(0.96%)和结核病患者中HIV阳性检出率(0.38%),差异有统计学意义(χ^(2)=169.571, P<0.01)。累计发现100例双重感染患者,抗结核治疗率99%(99/100),抗艾滋病病毒治疗率81%(81/100),联合开展抗艾滋病病毒和抗结核治疗率80%(80/100),结核病成功治疗率87.88%(87/99),死亡占11.11%(11/99)。结论:双向筛查在早期发现TB/HIV双重感染患者中具有十分重要的意义,应继续加大双重感染患者筛查力度,早期发现,早期治疗,同时依托基本公共卫生服务项目做好双感患者随访管理以及关怀服务,提高结核病成功治疗率,减少传染源和传播流行,动员艾滋病患者中结核菌潜伏感染者进行结核病预防性治疗,降低发病风险。
OBJECTIVE To analyze TB/HIV bidirectional screening data and treatment information of co-infection patients in Wanzhou district of Chongqing, and to provide reference for further improving the prevention and control strategy of TB/HIV co-infection in the area. METHODS The data of TB/HIV bidirectional screening in Wanzhou district from 2015 to 2020 was analyzed by descriptive epidemiological method. RESULTS From 2015 to 2020, 6 391 TB patients were newly registered, 4 494 were tested for HIV antibody, the HIV antibody detection rate was 70.75%, 17 were HIV-positive, and the HIV-positive detection rate was 0.38%;850 cases of newly detected HIV/AIDS patients were tested for tuberculosis, and the tuberculosis inspection rate was 92.79%(850/916),46 tuberculosis patients were found, the patient detection rate was 5.41%;among the HIV/AIDS patients who had been followed up,3 862 cases were tested for tuberculosis, and the tuberculosis inspection rate was 91.49%(3 862/4 221), 37 patients were found, and the detection rate of patients was 0.96%. The detection rate of tuberculosis in newly detected HIV/AIDS patients(5.41%) was higher than that of previously followed up HIV/AIDS patients(0.96%) and HIV positive rate of tuberculosis patients(0.38%), the difference was statistically significant(χ^(2)=169.571, P<0.01). A total of 100 patients with double infection were found, with anti-tuberculosis treatment rate of 99%(99/100) and anti-virus treatment rate of 81%(81/100), combined anti-tuberculosis and anti-tuberculosis treatment rate of 80%(80/100), successful treatment rate of 87.88%(87/99) and the death rate accounted for 11.11%(11/99).CONCLUSION Two-way screening in the early detection of TB/HIV double infection patients had very important significance, should continue to strengthen double infection screening, early detection, early treatment, relying on the basic public health services for double patients follow-up management and care services, improve TB successful treatment rate to reduce the source and transmission epidemic,mobilize HIV patients latent tuberculosis infection tuberculosis preventive treatment to reduce the risk.
作者
潘程程
张婷
邓云
王军
PAN Cheng-cheng;ZHANG Ting;DENG Yun;WANG Jun(Wanzhou District Center for Disease Control and Prevention,Chongqing,404100,China)
出处
《中国初级卫生保健》
2022年第5期55-57,65,共4页
Chinese Primary Health Care
基金
重庆市万州区科卫联合医学科研项目(wzstc-kw2021030)。
作者简介
通信作者:张婷,E-mail:717200935@qq.com。