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宫腔镜下冷刀分离术对宫腔粘连患者炎性因子水平及复发率的影响 被引量:7

Impact of Hysteroscopic Cold Knife Separation on Inflammatory Factor Levels and Recurrence Rate of Patients with Intrauterine Adhesions
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摘要 目的 探讨宫腔镜下冷刀分离术对宫腔粘连患者炎性因子水平及复发率的影响。方法 选取2018年6月至2020年5月我院收治的110例宫腔粘连患者,随机分为两组各55例。对照组行宫腔镜下电切术治疗,观察组行宫腔镜下冷刀分离术治疗,比较两组的炎性因子(CRP、 IL-6、 IL-8、 TNF-α)水平及复发率。结果 术后3 d,两组的CRP、 IL-6、 IL-8、 TNF-α水平均显著高于术前(P<0.05),但观察组的CRP、 IL-6、 IL-8、 TNF-α水平均显著低于对照组(P<0.05)。观察组术后3、 6、 12个月的复发率均显著低于对照组(P<0.05)。结论 宫腔镜下冷刀分离术治疗宫腔粘连可显著减轻患者炎性反应,降低复发率。 Objective To explore the impact of hysteroscopic cold knife separation on inflammatory factor levels and recurrence rate of patients with intrauterine adhesions. Methods 110 patients with intrauterine adhesions admitted to our hospital from June 2018 to May2020 were selected and randomly divided into two groups, with 55 cases in each group. The control group was treated with hysteroscopic electrotomy, and the observation group was treated with hysteroscopic cold knife separation. The levels of inflammatory factors(CRP, IL-6,IL-8 and TNF-α) and recurrence rates of the two groups were compared. Results At 3 days after surgery, the levels of CRP, IL-6, IL-8 and TNF-α in the two groups were significantly higher than those before surgery(P <0.05), but the levels of CRP, IL-6, IL-8 and TNF-α in the observation group were significantly lower than those in the control group(P <0.05). The recurrence rates at 3, 6 and 12 months after surgery in the observation group were significantly lower than those in the control group(P <0.05). Conclusions Hysteroscopic cold knife separation in the treatment of intrauterine adhesions can obviously relieve patients’ inflammatory response and reduce the recurrence rate.
作者 史靖 张一帆 SHI Jing;ZHANG Yifan(Department of Gynecology,Pingdingshan Maternal and Child Health Hospital,Pingdingshan 467000,China)
出处 《临床医学工程》 2022年第6期761-762,共2页 Clinical Medicine & Engineering
关键词 宫腔镜下冷刀分离术 宫腔粘连 炎性因子 复发率 Hysteroscopic cold knife separation Intrauterine adhesions Inflammatory factors Recurrence rate
作者简介 史靖(1985-),女,满族,河南平顶山人,本科学历,主治医师,研究方向:妇科相关疾病的诊治。
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