摘要
近年来诸多学者以中医药理论建立"病证结合"模型得到广泛应用。传统疾病造模方式叠加中医证候因素造模能较好模拟临床发病实际,因此建立"病证"模型更适用于现代中医药基础研究。湿热证模型是目前模型制作体系较成熟、评价较完备、应用较广泛的中医证候模型之一,已受到学者们广泛关注。文章就近年来湿热证"病证结合"模型生物学在炎症反应、肠道菌群、代谢组学、免疫平衡的研究现状展开综述,以期为同类研究提供借鉴参考。
In recent years, many scholars have established a ‘combination of disease and syndrome’ model based on the theory of traditional Chinese medicine(TCM), which has been widely used. Traditional disease modeling methods combined with TCM syndrome factor modeling can better simulate the actual clinical disease. Therefore, the establishment of a ‘disease syndrome’ model is more suitable for basic research in modern Chinese medicine. The damp-heat syndrome model is one of the TCM syndrome models with a relatively mature model making system, a relatively complete evaluation, and a wide range of applications. It has received extensive attention from scholars. This article reviews the research status of the model biology of damp-heat syndrome ‘combination of disease and syndrome’ in inflammatory response, intestinal flora, metabonomics and immune balance in recent years. The development of other correlations is expected to provide reference for similar research.
作者
买鹏宇
朱闽
叶斌
张泽朝
MAI Peng-yu;ZHU Min;YE Bin;ZHANG Ze-chao(Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530011,China;Guangxi University of Chinese Medicine,Nanning 530001,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2021年第12期7248-7251,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81660796,No.81860847)
广西自然科学基金项目(No.2018GXNSFAA281081)
广西研究生教育创新计划校级重点项目(No.YCSZ2018004)
广西一流学科建设项目(No.2019XK153)。
关键词
湿热证
病证结合
模型
生物学基础
研究进展
Damp-heat syndrome
Combination of disease and syndrome
Model
Biological basis
Research progress
作者简介
通信作者:朱闽,广西壮族自治区南宁市兴宁区华东路10号广西中医药大学附属瑞康医院皮肤性病科,邮编:530011电话:0771-2183035,E-mail:hnf22@126.com。
