摘要
高尿酸血症是由机体内嘌呤代谢紊乱和尿酸排泄减少引起血尿酸增高的疾病。近年来,研究报道茶叶及其功能成分(主要为茶多酚类和茶色素类化合物)通过抑制嘌呤代谢酶来减少尿酸的生成和调节尿酸转运蛋白来增加尿酸的排泄,从而发挥降尿酸作用。文章系统阐述了茶叶及其功能成分的降尿酸作用及作用机制,旨在为论证饮茶降尿酸和茶叶功能产品研发提供研究思路。
Hyperuricemia is a disease of increased blood uric acid caused by the disorder of purine metabolism and decreased uric acid excretion in the host.In recent years,studies have reported that tea and its functional components(mainly tea polyphenols and tea pigment compounds)inhibit purine metabolism enzymes to reduce the production of uric acid,and regulate uric acid transporter to increase the excretion of uric acid,thereby exerting a uric acid-lowering effect.This article systematically reviewed the uric acid-lowering effects of tea and its functional components and its mechanism of action,aiming to provide research ideas for the research and development of tea-drinking tea-lowering uric acid and tea functional products.
作者
周方
刘昌伟
曾鸿哲
李娟
陈金华
王英姿
谭斌
黄建安
刘仲华
ZHOU Fang;LIU Chang-wei;ZENG Hong-zhe;LI juan;CHEN Jin-hua;WANG Ying-zi;TAN Bin;HUANG Jian-an;LIU Zhong-hua(Key Lab of Education Ministry of Hunan Agricultural University for Tea Science,Changsha 410128,China;National Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients,Changsha 410128,China;Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients,Changsha 410128,China)
出处
《中国茶叶加工》
2022年第1期24-28,共5页
China Tea Processing
基金
国家重点研发计划(2017YFD0400803,2018YFC1604405)
国家茶叶产业技术体系研究项目(CARS-19)
国家自然科学基金项目(31471590,31100501)。
关键词
茶
功能成分
降尿酸
作用机制
Tea
Functional components
Reduce uric acid
Mechanism
作者简介
周方(1996-),男,湖南南县人,博士研究生,主要从事茶叶深加工与功能成分利用;通讯作者:刘仲华,larkin-liu@163.com。
