摘要
目的观察电针治疗职业性噪声聋(ONID)伴发抑郁症状的临床疗效。方法将57例ONID伴发抑郁症状患者作为研究对象,随机分为治疗组28例和对照组29例。对照组采用常规西医治疗,治疗组在对照组基础上加用电针治疗。观察两组治疗前后汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、焦虑自评量表(SAS)、汉密尔顿焦虑量表(HAMA)、耳鸣残疾量表(THI)、匹兹堡睡眠质量指数(PSQI)量表评分及纯音测听听阈的差异,并比较两组临床疗效。结果治疗组总有效率为82.1%,对照组为10.3%,差异有统计学意义(P<0.05)。对照组治疗后HAMD总分、体质量和认知障碍这2个因子评分有明显改善,治疗组HAMD总分及各因子的评分均较治疗前降低,差异有统计学意义(P<0.05);治疗组在改善HAMD总分和焦虑/躯体化、认知障碍、迟缓及睡眠障碍4个因子评分优于对照组(P<0.05)。治疗组治疗后SDS评分、SAS评分、HAMA总分明显降低(P<0.05);治疗组SDS、SAS、HAMA评分改善较对照组明显,差异有统计学意义(P<0.05)。两组治疗后THI总分均得到了改善,对照组体现在功能性评分的降低,而电针治疗组则表现在情感性评分的降低上,差异有统计学意义(P<0.05)。治疗组治疗后PSQI评分优于治疗前,治疗组PSQI评分的改善优于对照组,差异有统计学意义(P<0.05)。两组治疗后右耳语频听阈及双耳高频听阈均有改善(P<0.05)。结论电针可显著减轻ONID伴发抑郁症状患者的抑郁、焦虑程度,并可明显改善患者的睡眠状态。
Objective To investigate the clinical efficacy of electroacupuncture for occupational noise-induced deafness(ONID)with depressive symptoms.Methods Fifty-seven ONID patients with depressive symptoms were enrolled as subjects and randomized to a treatment group(28 cases)and a control group(29 cases).The control group received conventional western medical treatment and the treatment group,electroacupuncture in addition.The Hamilton Depression Scale(HAMD)score,the self-rating depression scale(SDS)score,the self-rating anxiety scale(SAS)score,the Hamilton Anxiety Scale(HAMA)score,the tinnitus handicap inventory(THI)score and the Pittsburgh Sleep Quality Index(PSQI)score were recorded and pure-tone audiometry thresholds were examined in the two groups before and after treatment.The clinical therapeutic effects were compared between the two groups.Results The total efficacy rate was 82.1%in the treatment group and 10.3%in the control group with a statistically significant difference(P<0.05).After treatment,the HAMD score and the body mass and cognitive impairment subscores improved significantly in the control group and the HAMD score and all item subscores decreased in the treatment group compared with before with statistically significant differences(P<0.05).The HAMD score and the anxiety/somatization,cognitive disorder,retardation and dyssomnia subscores improved more in the treatment group than in the control group(P<0.05).After treatment,the SDS score,the SDS score and the HAMD score decreased significantly in the treatment group(P<0.05)and improved more significantly than in the control group with statistically significant differences(P<0.05).After treatment,the PSQI score was better in the treatment group(P<0.05)compared with before and improved more than in the control group with statistically significant differences(P<0.05).After treatment,the THI score improved in the two groups,and the function subscore decreased in the control group,while the emotion subscore decreased in the treatment group with statistically significant differences(P<0.05).Speech frequency thresholds in the right ear and high-frequency hearing thresholds in both ears improved in the two groups after treatment(P<0.05).Conclusions Electroacupuncture can markedly reduce the degree of depression and anxiety and improve sleep status in ONID patients with depressive symptoms.
作者
邓小峰
罗巧
郭集军
杨爱初
赖丽丽
徐琳
夏丽华
DENG Xiao-feng;LUO Qiao;GUO Ji-jun;YANG Ai-chu;LAI Li-li;XU Lin;XIA Li-hua(Guangdong Hospital of Occupational Disease Prevention and Treatment/Guangdong Key Laboratory of Occupational Disease Prevention and Treatment,Guangzhou 510300,China)
出处
《上海针灸杂志》
2021年第11期1368-1374,共7页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家临床重点专科建设项目(2011-09)
广东省中医药局面上科研项目(20191048)
广东省职业病防治重点实验室(2017B030314152)。
关键词
电针
针药并用
抑郁症
职业病
聋
汉密尔顿抑郁量表
抑郁自评量表
耳鸣残疾量表
匹兹堡睡眠质量指数
Electroacupuncture
Acupuncture medication combined
Depressive disorder
Occupational diseases
Deafness
Hamilton Depression Scale
Self-rating depression scale
Tinnitus handicap inventory
Pittsburgh Sleep Quality Index
作者简介
邓小峰(1981—),女,主任医师,博士,Email:fenge2005@163.com。