摘要
Recently,traditional Chinese medicine-based treatment has succeeded in fighting coronavirus disease 2019(COVID-19),and Rhizoma polygonati(Huangjing)has been one of the recommended components.Its processed products play antidiabetic,antiviral,antitumor,antioxidation,antifatigue,antiaging,and immune enhancement roles.The climate in Mount Tai is mild,and the dense forest is suitable for the growth of Rhizome polygonati,which has gradually evolved into a unique specie.Considering the important medicinal value and pleasant taste of Mount Tai-Rhizoma polygonati,various healthy and functional food products,controlled by quality markers with anti-COVID-19 potential,as well as emergency foods can be developed.The study aimed to review current evidence on the nutritional value of Rhizoma polygonati from Mount Tai and its usefulness as a traditional Chinese medicine,source of herbzyme,and potential remediating agent for COVID-19 and food shortage.Most recent findings regarding herbal nanomedicine have revealed that nanoscale chemical compounds are potentially efficient in drug delivery or nanozyme catalysis upon bioprocessing.Nanoflower structure is found in processed Rhizoma polygonati by self-assembly and has wide application in enzymatic events,particularly nanoscale herbzyme.The novel findings regarding Mount Tai-Rhizoma polygonati could enhance its novel applications in chronic and hidden hunger,clinical nanomedicine,and as an anti-COVID-19 agent.
近年来,中药治疗在抗击COVID-19取得成功疗效,黄胡连(黄精)的加工产品具有抗糖尿病、抗病毒、抗肿瘤、抗氧化、抗疲劳、抗衰老和增强免疫的作用,是推荐成分之一。泰山气候温和,森林茂密适合多根根茎的生长,已逐渐进化为一种独特的物种。考虑到泰山的重要药用价值和宜人的口感,可以开发出具有抗COVID-19潜力的质量标志物控制的各种健康、功能食品和应急食品。本研究旨在回顾目前泰山黄精的营养价值及其作为中药、草药酶来源、治疗COVID-19和食物短缺的潜在治疗剂的证据。关于草药纳米医学的最新发现表明,纳米级化合物在药物传递或纳米酶催化生物加工中有潜在的效率。
作者
Lazzat Nurtay
Qinglei Sun
Chenglin Mu
Zhongshan Cao
Qian Wang
Zongsuo Liang
Cuiping Ma
Xugang Li
Amr Amin
Yingqiu Xie
Lazzat Nurtay;孙庆雷;牟成林;曹仲山;王倩;梁宗锁;马翠萍;李旭刚;Amr Amin;Yingqiu Xie(纳扎尔巴耶夫大学科学与人文学院生物系,哈萨克斯坦共和国努尔苏丹;山东省大型精密分析仪器应用技术重点实验室,山东省分析测试中心,齐鲁工业大学(山东省科学院),济南;山东农业大学生命科学学院农业生物学国家重点实验室农业生物学联合研究中心,泰安;山东泰尚黄精生物科技有限公司,黄精产业研究院,泰安;浙江理工大学生命科学与医药学院,杭州;青岛科技大学海洋科学生物工程研究中心,青岛科技大学海洋科学与生物工程学院,青岛;阿拉伯联合酋长国大学生物系,15551,阿拉伯联合酋长国;美国芝加哥大学,IL60637,美国)
基金
financially supported by Shandong Taishanghuangjing Biotechnology Co.Ltd.
received Faculty-Development Competitive Research Grants Program of Nazarbayev University(ID:16797152,ie,15798117(110119FD4531)to Yingqiu Xie,and ID:16796808,ie,15874919(110119FD4542)to Haiyan Fan and Yingqiu Xie)
2019 Asian Universities Alliance(AUA)fellowship of United Arab Emirates University(UAEU)to Yingqiu Xie and Amr Amin.
作者简介
Lazzat Nurtay,contributed equally to this work;Qinglei Sun,contributed equally to this work;Corresponding author:Yingqiu Xie,School of Sciences and Humanities,Nazarbayev University,Nur-Sultan 010000,Republic of Kazakhstan,E-mail:yingqiu.xie@nu.edu.kz;Corresponding author:Xugang Li,Sino-German Joint Research Center on Agricultural Biology,State Key Laboratory of Crop Biology,College of Life Sciences,Shandong Agricultural University,Tai’an 271018,China,E-mail:xgli@sdau.edu.cn.
