摘要
目的分析上海闵行区变应性鼻炎(AR)患者过敏原分布情况。方法选取2019年1-12月在复旦大学附属上海市第五人民医院耳鼻咽喉科就诊的血清过敏原检测结果中至少有一种特异性免疫球蛋白E(IgE)为阳性的319例AR患者,比较不同性别、年龄、季节其过敏原阳性率的分布差异。结果319例AR患者年龄高峰为18~45岁,其中总IgE阳性者为197例(61.76%)。排名前3位的吸入性过敏原分别为尘螨(246例,77.12%)、猫毛(36例,11.29%)、屋尘(25例,7.84%)。最常见的食入性过敏原为蟹(25例,7.84%),其次为羊肉(17例,5.33%)。屋尘、艾蒿、羊肉的特异性IgE阳性率在不同季节之间差异有统计学意义(P<0.05),尘螨、猫毛、蟹、黄豆、海鱼、狗上皮的阳性率在不同季节差异无统计学意义(P>0.05)。狗上皮阳性率在不同年龄组间差异有统计学意义(P<0.05)。结论上海闵行区AR患者以青年为主,最常见的过敏原为尘螨,应以此为基础积极展开宣传、防治等工作。
Objective To study the distribution of allergens in patients with allergic rhinitis(AR)in Minhang district of Shanghai.Methods A total of 319 patients with AR who had at least one specific IgE(sIgE)positive in the allergen test results in the Department of Otorhinolaryngology of the Fifth People′s Hospital Affiliated to Fudan University in 2019 were selected.The distribution differences of allergen positive rates in different genders,ages,and seasons were compared.Results The peak age of 319 patients with AR was 18-45 years old,of which 197 patients(61.76%)were positive for total IgE.The top three inhaled allergens were dust mites(246 cases,77.12%),cat hair(36 cases,11.29%),and house dust(25 cases,7.84%).The most common ingested allergen was crab(25 cases,7.84%),followed by lamb(17 cases,5.33%).The positive rates of house dust,mugwort,and lamb were statistically different in different seasons(P<0.05),while the positive rates of dust mites,cat hair,crab,soybean,marine fish,and dog epithelium were not statistically different in different seasons(P>0.05).The positive rate of dog epithelium was significantly different among different age groups(P<0.05).Conclusion AR patients in Minhang district of Shanghai are mainly young people,and the most common allergen is dust mites.Active publicity and prevention treatment should be carried out on this basis.
作者
王炎
田露芳
龚静蓉
庞宇峰
毛会军
WANG Yan;TIAN Lufang;GONG Jingrong;PANG Yufeng;MAO Huijun(Department of Otorhinolaryngology,Shanghai 200240,China;Department of Clinical Laboratory,Shanghai Fifth People′s Hospital Affiliated to Fudan University,Shanghai 200240,China)
出处
《检验医学与临床》
CAS
2021年第13期1839-1842,共4页
Laboratory Medicine and Clinic
基金
上海市闵行区自然科学研究课题(2018MHZ051)。
关键词
过敏原
变应性鼻炎
上海
allergens
allergic rhinitis
Shanghai
作者简介
王炎,女,医师,主要从事变应性鼻炎相关研究;通信作者:田露芳,E-mail:tianlufang2006@163.com。
