摘要
目的分析2010—2016年广西肿瘤登记地区肝癌发病和死亡特征及其变化趋势,为广西制定肝癌防控措施提供依据。方法收集2010—2016年广西肿瘤登记地区上报的恶性肿瘤发病与死亡资料,计算肝癌发病率、死亡率、构成比、0~74岁累积率、35~64岁截缩率,按地区(城市/农村)、性别和年龄分层。采用2000年中国人口普查和Segi′s世界人口计算年龄标准化率。采用Joinpoint模型对肝癌发病率和死亡率进行趋势分析。结果2010—2016年广西肿瘤登记地区肝癌发病率为41.79/10万,中标率为34.86/10万,世标率为33.45/10万,0~74岁累积率为3.79%,35~64岁截缩率为68.60/10万;死亡率为34.56/10万,中标率为28.63/10万,世标率为27.63/10万,0~74岁累积率为3.12%,35~64岁截缩率为54.48/10万;男性发病率和死亡率均高于女性,农村地区高于城市地区。2010—2016年广西肿瘤登记地区肝癌发病和死亡水平呈明显上升趋势,发病率的APC为5.38%(95%CI:2.56%~8.29%,P<0.05),死亡率的APC为9.23%(95%CI:3.83%~14.92%,P<0.05)。结论2010—2016年广西肿瘤登记地区肝癌发病率和死亡率呈上升趋势,应针对肝癌致病因素和流行特征采取有效措施予以防控,35岁及以上男性(尤其农村)是开展早期筛查和干预的重点人群。
ObjectiveTo analyze the characteristics and trends of the incidence and mortality of liver cancer in the cancer registration areas in Guangxi from 2010 to 2016,and to provide the basis for developing the prevention and control measures of liver cancer in Guangxi.MethodsThe incidence and mortality data of cancer in the cancer registration areas in Guangxi from 2010 to 2016 were collected,and the incidence rate,mortality rate,proportionate,cumulative rate(0-74 years old)and truncated rate(35-64 years old)were calculated by areas(urban/rural),gender and age stratification.The age-standardized rates were calculated by the 2000 national census(ASR China)and Segi′s standard population(ASR world).The trend of incidence and mortality of liver cancer was analyzed by Joinpoint model.ResultsFrom 2012 to 2016,the incidence of liver cancer in Guangxi was 41.79/105,the ASR China 34.86/105,the ASR world 33.45/105,the cumulative rate(0-74 years old)3.79%,and the truncated rate(35-64 years old)68.60/105.The mortality rate was 34.56/105,the ASR China 28.63/105,the ASR world 27.63/105,the cumulative rate(0-74 years old)3.12%,and the truncated rate(35-64 years old)54.48/105.The incidence and mortality rates of males were higher than those of females,and those in rural areas were higher than those in urban areas.From 2010 to 2016,the incidence and mortality levels of liver cancer in Guangxi cancer registration areas showed a significantly increasing trend,with the incidence and mortality APC of 5.38%(95%CI:2.56%-8.29%,P<0.05)and 9.23%(95%CI:3.83%-14.92%,P<0.05),respectively.ConclusionsFrom 2010 to 2016,the incidence and mortality of liver cancer in Guangxi cancer registration areas showed an increasing trend.Therefore,effective measures should be taken to prevent and control liver cancer according to the pathogenic factors and epidemic characteristics of liver cancer.Men aged 35 and above(especially in rural areas)are the key population for early screening and intervention.
作者
李秋林
曹骥
容敏华
周子寒
余红平
葛莲英
余家华
LI Qiulin;CAO Ji;RONG Minhua;ZHOU Zihan;YU Hongping;GE Lianying;YU Jiahua(Guangxi Medical University Cancer Hospital,Guangxi Cancer Center,Guangxi Office for Cancer Prevention and Control,Nanning 530021,China)
出处
《中国癌症防治杂志》
CAS
2021年第2期138-143,共6页
CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT
基金
国家自然科学基金项目(81860596)
广西卫生和计划生育委员会自筹经费科研课题(Z20180649)。
关键词
肝癌
发病率
死亡率
肿瘤登记
广西
Liver cancer
Incidence
Mortality
Cancer registration
Guangxi
作者简介
通信作者:余家华,E⁃mail:gxzlfb@163.com。
