摘要
目的:分析中国东部岛屿地区恶性肿瘤的发病与死亡特征并与同期中国恶性肿瘤死亡数据进行比较,为岛屿地区制定肿瘤防治措施提供科学依据。方法:根据舟山市岱山县疾病控制预防中心收集的2014—2019年浙江省舟山市岱山县的恶性肿瘤发病和死亡资料,按照性别分层,分别计算恶性肿瘤的粗发病率、粗死亡率和前10位恶性肿瘤顺位等,并且以Segi’s世界标准人口年龄构成作为标准,计算标化发病率和标化死亡率。随后,将所得分析数据与同期全国癌症死亡数据进行比较,用SPSS软件进行卡方检验,分析2者标化死亡率之间的差异,以P<0.05为差异有统计学意义。结果:2014—2019年岱山县恶性肿瘤发病总计7305例,粗发病率为662.39/10万人年,标化发病率为306.81/10万人年,75~79岁年龄组的总发病率最高;发病前5位的恶性肿瘤分别为肺癌(27.15%)、胃癌(12.76%)、肝癌(10.95%)、结直肠癌(6.92%)和乳腺癌(5.42%),标化发病率分别为75.09/10万人年、32.06/10万人年、31.01/10万人年、17.81/10万人年和18.36/10万人年。2014—2019年岱山县恶性肿瘤死亡总计3412例,粗死亡率为309.39/10万人年,标化死亡率为122.73/10万人年,80~84年龄组总死亡率最高;死亡前5位的恶性肿瘤分别为肺癌(24.94%)、肝癌(18.64%)、胃癌(17.00%)、结直肠癌(7.56%)和食道癌(5.72%),标化死亡率分别为29.65/10万人年、24.97/10万人年、19.01/10万人年、8.75/10万人年和6.60/10万人年。2014—2019年6年间岱山县恶性肿瘤总标化死亡率显著高于全国恶性肿瘤总标化死亡率(100.34/10万人年)(P<0.001)。其中,岱山县的胃癌、肝癌和结直肠癌的标化死亡率显著高于全国水平(胃癌:12.46/10万人年;肝癌:16.45/10万人年;结直肠癌:6.63/10万人年)(P<0.01)而肺癌和食管癌的标化死亡率与全国标化死亡率(肺癌:28.06/10万人年;食管癌:7.61/10万人年)间的差异无统计学意义。结论:2014—2019年肺癌、胃癌、肝癌和结直肠癌是浙江省舟山市岱山县发病率和死亡率较高的癌种。其中,胃癌、肝癌和结直肠癌的标化死亡率显著高于同期全国水平,应作为重点防治癌种。
Objective:To provide scientific basis for prevention and control measures of island regions through analyzing the characteristics of malignant tumor incidence and mortality in eastern island areas of China and comparing the data with the national cancer mortality data in the same period.Methods:Using the incidence and mortality data of malignant tumor in Daishan county,Zhoushan collected by the Daishan Center for Disease Control and Prevention(CDC)from 2014 to 2019,which was stratified by gender,the crude incidence rates(CIR)and crude mortality rates(CMR)were calculated,and the top 10 malignant tumors with the highest incidence or mortality rates were then ranked.The Segi’s world standard population was used to calculate the agestandardized incidence rate(ASIR)and age-standardized mortality rate(ASMR).The local data were compared with the national cancer mortality data from 2014 to 2019,and Chi-square test was used to analyze the differences between these two sets of data using the SPSS software.The difference was considered statistically significant when P<0.05.Results:There was a total of 7305 incidence cases of malignant tumors in Daishan county,Zhoushan from 2014 to 2019.The CIR was 662.39/10^(5) and the ASIR was 306.81/10^(5).Notably,the CIR was the highest in the age group of 75-79 years old.The top 5 malignant tumors with the highest incidence rates were lung cancer(27.15%),gastric cancer(12.76%),liver cancer(10.95%),colorectal cancer(6.92%)and breast cancer(5.42%),whose ASIR were 75.09/10^(5),32.06/10^(5),31.01/10^(5),17.81/10^(5) and 18.36/10^(5),respectively.There was a total of 3412 mortality cases of malignant tumors in Daishan county,Zhoushan from 2014 to 2019.The CMR was 309.39/10^(5) and the ASMR was 122.73/10^(5).Notably,the CMR was the highest in the age group of 80-84 years old.The top 5 malignant tumors with the highest mortality rates were lung cancer(24.94%),liver cancer(18.64%),gastric cancer(17.00%),colorectal cancer(7.56%)and esophageal cancer(5.72%),whose ASMR were 29.65/10^(5),24.97/10^(5),19.01/10^(5),8.75/10^(5) and 6.60/10^(5),respectively.The total ASMR of malignant tumors in Daishan county,Zhoushan was higher than national total ASMR from 2014 to 2019(100.34/10^(5))(P<0.001).Specifically,the ASMR of gastric cancer,lung cancer and colorectal cancer in Daishan county were significantly higher than national levels(gastric cancer:12.46/10^(5);liver cancer:16.45/10^(5);colorectal cancer:6.63/10^(5))(P<0.01),whereas no significant difference in the ASMR of lung cancer and esophageal cancer between Daishan county and the whole nation(lung cancer:28.06/10^(5);esophageal cancer:7.61/10^(5))was observed.Conclusion:Lung cancer,gastric cancer,liver cancer and colorectal cancer were malignant tumors with higher incidence and mortality rates in Daishan county,Zhoushan from 2014 to 2019.Particularly,the ASMR of gastric cancer,liver cancer and colorectal cancer were significantly higher than the national levels,and these malignant tumors should be considered as the major focus of cancer prevention and control.
作者
沈佳莹
蒋栋铭
叶凌
朱小琼
刘吉洛
陈一凡
王坤炎
曹广文
SHEN Jiaying;JIANG Dongming;YE Ling;ZHU Xiaoqiong;LIU Jiluo;CHEN Yifan;WANG Kunyan;CAO Guangwen(Tongji University School of Medicine,Shanghai 200331,China;Center for Disease Control and Prevention,Daishan County,Zhoushan 316299,Zhejiang Province,China;Anhui Medical University,Hefei 230032,Anhui Province,China;Department of Epidemiology,Naval Medical University,Shanghai 200433,China)
出处
《肿瘤》
CAS
北大核心
2023年第2期97-105,共9页
Tumor
基金
上海市公共卫生体系建设三年行动计划(GWV-10.1-XK17)
关键词
恶性肿瘤
登记
发病率
死亡率
岱山县
浙江省
Malignant tumor
Registries
Incidence
Mortality
Daishan county
Zhejiang province
作者简介
沈佳莹,contributed equally to this article;蒋栋铭,contributed equally to this article;Correspondence to:曹广文,E-mail:gcao@smmu.edu.cn;Correspondence to:王坤炎,E-mail:737180863@qq.com*These two authors
