摘要
目的探讨后腹腔镜肾盂切开取石术对男性肾盂结石患者血液流变学、性功能等指标的影响。方法选取2016年10月至2019年1月广安市人民医院诊治的82例男性肾盂结石患者作为研究对象。按照随机数字表法分为研究组(n=41)与对照组(n=41)。对照组采取经皮肾镜取石术(PCNL),研究组采取后腹腔镜肾盂切开取石术(RLP)。统计两组应激反应、血液流变学、性功能指标评分,以及并发症情况。结果术后1 d两组皮质醇(Cor)、去甲肾上腺素(NE)、促肾上腺皮质激素(ACTH)水平较术前明显增高,但研究组各指标水平低于对照组,差异具有统计学意义(P<0.05)。术后1 d两组全血低切及高切黏度、血浆黏度、血细胞比容均较术前明显增高,但研究组各指标水平低于对照组,差异具有统计学意义(P<0.05)。术后2个月两组国际前列腺症状评分(IPSS)、中国早泄患者性功能评价表-5(CIPE-5)评分较术前增高,而国际勃起功能指数5(IIEF-5)评分较术前降低,差异具有统计学意义(P<0.05),但组间比较,差异无统计学意义(P>0.05);术后4个月两组IPSS、CIPE-5较术前降低,IIEF-5评分较术前升高,差异具有统计学意义(P<0.05),但组间比较,差异无统计学意义(P>0.05)。研究组并发症发生率低于对照组,差异具有统计学意义(P<0.05)。结论采取RLP治疗肾盂结石创伤小,围术期应激反应程度较轻,可减少对血液流变学及性功能造成的影响,利于术后性功能早期康复,且并发症少,具有安全性。
Objective To explore the effect of retroperitoneal laparoscopic pyelolithotomy on hemorheology and sexual function of male pyelolithiasis.Methods 82 male patients with renal pyelolithiasis diagnosed and treated in Guang′an People′s Hospital from October 2016 to January 2019 were selected as the research subjects,and divided into study group(n=41)and control group(n=41)according to random number table method.The control group was treated with percutaneous nephrolithotomy(PCNL),and the study group with retroperitoneal laparoscopic pyelolithotomy(RLP).The stress response,hemorheological status,sexual function score and complications of the two groups were analyzed.Results The levels of Cor,NE and ACTH in the two groups 1 day after surgery were significantly higher than those before surgery,but the levels of each index in the study group were lower than those in the control group,with statistical significance(P<0.05).On day 1 after surgery,the whole blood low-cut and high-cut viscosity,plasma viscosity and hematocyte specific volume in both groups were significantly higher than those before surgery,but the levels of each index in the study group were lower than those in the control group,with statistical significance(P<0.05).Two months after surgery,IPSS and CIPE-5 in both groups was higher than those before surgery,while IIEF-5 scores were lower than those before surgery,the difference was statistically significant(P<0.05),but there was no statistically significant difference between the two groups(P>0.05).Four months after surgery,IPSS and CIPE-5 of the two groups was lower than those before surgery,while IIEF-5 scores were higher than those before surgery,the difference was statistically significant(P<0.05),but there was no statistically significant difference between the two groups(P>0.05).The complication rate in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusions RLP in treatment of renal pelvic calculi has less trauma and less perioperative stress response,which can reduce the impact on hemorheology and sexual function,and is conducive to early recovery of sexual function after operation,with fewer complications and safety.
作者
牟健
MOU Jian(Department of Urology,Guang′an People′s Hospital,Guang′an 638000,Sichuan,China)
出处
《中国性科学》
2021年第2期29-33,共5页
Chinese Journal of Human Sexuality
关键词
后腹腔镜肾盂切开取石术
肾盂结石
性功能
应激反应
血液流变学
Retroperitoneal laparoscopic pyelolithotomy
Pyelolithiasis
Sexual function
Stress response
Hemorheology
作者简介
通讯作者:牟健,E-mail:zeojhp@163.com。
