摘要
目的:探讨RLP治疗肾盂结石的中远期随访效果。方法:以攀枝花市中心医院2014年2月~2015年10月收治的82例肾盂结石患者为对象,依据治疗方案不同分为对照组(接受PCNL治疗,n=40)和研究组(实施RLP治疗,n=42),比较两组手术相关指标、临床疗效,观察两组手术前后肾功能(BUN、Ccr、24h尿蛋白定量)变化,比较两组远期并发症发生情况。结果:研究组手术时间与对照组相比较差异无统计学意义(P>0.05);与对照组相比较,研究组术中出血量、住院时间明显少/短,术后输血率明显低(P<0.05);研究组治疗后总有效率88.10%明显高于对照组70.00%(P<0.05);术前两组BUN、24h尿蛋白量、Ccr相比较差异无统计学意义(P>0.05),与术前相比较,术后仅对照组BUN、24h尿蛋白量显著升高,Ccr显著降低,且术后对照组各项指标变化较研究组显著,差异有统计学意义(P<0.05);术后研究组远期并发症发生率28.57%较对照组50.00%显著低,差异有统计学意义(P<0.05)。结论:在肾盂结石治疗中,RLP较PCNL具有创伤小、恢复快、中期手术效果佳、远期并发症少、对肾功能损伤小的显著优势,更适于临床推广应用。
Objective:To explore the middle-term and long-term follow-up effects of retroperitoneal laparoscopic pyelolithotomy(RLP)in the treatment of renal pelvis calculi.Methods:Eighty-two patients with renal pelvis calculi treated in our hospital during the period from February 2014 to October 2015 were selected as the subjects.According to different treatment methods,the patients were divided into control group[treated by percutaneous nephrolithotomy(PCNL),n=40]and study group(treated by RLP,n=42).Operation associated indicators and the clinical curative effect were compared between the two groups.Changes in renal function[blood urea nitrogen(BUN),creatinine clearance rate(Ccr),24 hurine protein quantitation]in the two groups before and after operation were observed,and the incidence of long-term complications was compared between the two groups.Results:There was no significant difference in the operation time between the two groups(P>0.05).The intraoperative blood loss,length of hospital stay and postoperative blood transfusion rate in the study group were significantly less/shorter/lower than those in the control group(P<0.05).After treatment,the total treatment effective rate in the study group was significantly higher than that in the control group(88.10% vs.70.00%)(P<0.05).There were no significant differences in BUN,24 hurinary protein quantitation and Ccr between the twogroups before operation(P>0.05).After operation,BUN and 24 hurinary protein quantitation were increased significantly while Ccr was decreased significantly only in the control group,and changes in the indexes were more obvious in the control group than in the study group(P<0.05).The incidence of long-term complications in the study group was significantly lower than that in the control group(28.57% vs.50.00%)(P<0.05).Conclusions:Compared with PCNL,RLP has the advantages of small trauma,fast recovery,good middle-term operation effects,few complications and little damage to renal function in the treatment of renal pelvis calculi.
出处
《微创泌尿外科杂志》
2018年第1期19-22,共4页
Journal of Minimally Invasive Urology
关键词
肾盂结石
后腹腔镜肾盂切开取石术
经皮肾镜碎石取石术
中远期疗效
renal pelvis calculi
retroperitoneal laparoscopic nephrolithotomy
percutaneous nephrolithotomy
middle-term and long-term curative effect
