摘要
目的将脑功能指标客观定量测量与9项病例健康问卷(PHQ-9)、7项广泛性焦虑(GAD-7)和躯体化症状自评量表(SSS)三种量表联合应用对患者焦虑抑郁的评估结果进行对比,为心脏康复患者筛查、术后患者焦虑和抑郁的评估提供一种新的客观定量评测手段.方法对阜外医院心内科通过简单随机抽样法抽取的93例拟行冠状动脉支架置入手术前患者进行PHQ-9、GAD-7和SSS的评估.根据量表评分结果将患者分为有焦虑抑郁组和无焦虑抑郁组两组,分别对两组患者的脑功能指标进行测量,分析两组患者的脑功能指标是否存在显著差异,并分析两种测量结果的一致性.结果根据主观量表PHQ-9、GAD-7总分进行分组,共分为两组:焦虑抑郁组39例(41.94%,PHQ-9≥5分或GAD-7≥5分),无焦虑抑郁组54例(58.06%,PHQ-9<5分且GAD-7<5分).焦虑抑郁组脑指标内专注为39.00±9.89,无焦虑抑郁组脑指标内专注为22.78±11.98,两组比较差异有统计学意义(P<0.05).脑功能指标内专注与PHQ-9的Spearman相关系数为0.5310(P<0.01),与GAD-7的相关系数是0.5378(P<0.01);故采用内专注筛查入选者焦虑抑郁(内专注>30为有焦虑抑郁组,内专注≤30为无焦虑抑郁组),结果显示有焦虑抑郁的51例(54.84%),无焦虑抑郁的42例(45.16%),总符合率是74.19%.两种方法的诊断结果进行Spearan相关分析,相关系数为0.5085,差异有统计学意义(P<0.01),一致性很好.结论脑功能指标与常规量表作为评测焦虑抑郁的两种方法,二者具有一致性;脑功能客观定量指标将有助于对焦虑、抑郁患者的临床评估.
Objective To compare the resuts of the ssessment of anxiety and depression in patients by combining objective measurement and conventional 3 scales of 9-iems patient health questionnaire(PHQ-9),the 7-item generalized anxiety disorder(GAD-7)and the self-rating scale of somatization symptoms(SSS),so as to provide a new objective and quantitative assessment for the screening of cardiac rechabilitation patients and the asessment of anxiety and depression in the postoperative patients.Methods Informed consent and self-completion of questionnaires were used to assess the PHQ-9,GAD-7 and sss in 93 patients randomly selected from the Department of Cardiology of Fuwai Hospial before the proposed coronary artry stenting surgery.The patients were divided into two groups with and w ithout anxiety and depression according to the results of the scale score;the brain function indexes of the two groups were measured separately to analyze whether there were significant differences between the two groups and the consistency of the two measurements.Results The groups were divided into two groups according to the subjective scale PHQ-9 and GAD-7 total scores:39 cases in the anxiety-depression group(41.94%。PHQ-9>5 or GAD-725)and 54 cases in the no-anxiety-depression group(58.06%,PHQ-9<5 and GAD-7<5).Brain indicators was 39.00±9.89 in the anxiety depression group and 22.78±11.98 in the no-anxiety-depression group and the dfference betwcen the two groups was stistically significant(P<0.05).The Spearman correlation cofficient of brain function indcx intemal focus and PHQ-9 was 0.5310(P<0.01)and the correlation cofficient with GAD-7 was 0.5378(P<0.01);so the internal focus was used to screen for anxiety and depression(intermal focus>30 for the group with anxiety and depression and intermal focus≤30 for the group without anxiety and depression)and the results showed that there were 51 cases(54.84%)of anxiety and depression and 42 cascs(45.16%)without anxiety and depression;the overall compliance rate was 74.19%,Spearman corrclation analysis was performed on the diagnostie results of the two methods and the correlation cofficient was 0.5085,with a statistically sigmificant difference(P<0.01)and good agreement.Conclusion Brain function indicators and conventional scales are consistent to assess anxiety and depression;brain function objective quantitative indicators will help in the elinical assment of anxious and depressed patients.
作者
李海霞
于欣
田艳蒙
傅建平
吴永健
LI Hai-xia;YU Xin;TIAN Yan-meng;FU Jian-ping;WU Yong-jian(Cardiovascular Internal Medicine Department,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100054,China;Cardiovascular Internal Medicine Department,Fuwai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China)
出处
《中国心血管病研究》
CAS
2020年第10期906-909,共4页
Chinese Journal of Cardiovascular Research
基金
国家自然科学基金资助项目(81973682、81303132)
中国中医科学院基本科研业务费自主选题项目(Z070803)
中药量效关系的自适应设计-贝叶斯预测模型预测研究(Z0254)。
作者简介
通信作者:吴永健,E-mail:liruijie168@vip.sina.com。
