摘要
目的探讨保留乳头乳晕和传统的乳腺癌改良根治术治疗乳腺癌的临床效果。方法将81例乳腺癌患者根据手术方式的不同分为观察组(n=47)和对照组(n=34)。观察组给予保留乳头乳晕的乳腺癌改良根治术,对照组给予传统的乳腺癌改良根治术。比较两组患者的手术相关指标、负性情绪、生存质量、复发转移情况和不良反应发生情况。结果观察组患者的手术时间明显长于对照组,术中出血量明显多于对照组(P﹤0.01)。术后6个月,两组患者的焦虑自评量表(SAS)、抑郁自评量表(SDS)评分均低于本组术前,且观察组的SAS、SDS评分均明显低于对照组(P﹤0.01)。术后6个月,观察组患者的乳腺癌治疗功能评价系统(FACT-B)评分明显高于对照组(P﹤0.01)。两组患者复发转移、不良反应的发生率比较,差异均无统计学意义(P﹥0.05)。结论保留乳头乳晕的乳腺癌改良根治术治疗乳腺癌有较好的临床效果,值得临床应用。
Objective To explore the clinical effect of nipple-and areola-sparing modified mastectomy and traditional modified radical mastectomy in the treatment of breast cancer.Method A total of 81 cases of patients with breast cancer were included in the analysis and divided by respective surgeries administered as study group(n=47)and control group(n=34).The study group was administered with modified radical mastectomy with nipple and areola preservation,while traditional modified radical mastectomy was performed in control group.The operative indicators,negative emotions,quality of life(QOL),occurrence of recurrence and metastasis as well as adverse reactions were compared between the two groups.Result The operative time was longer and volume of hemorrhage during surgery were greater in study group versus control group(P<0.01).At 6 months post-surgery,the self-rating anxiety scale(SAS),self-rating depression scale(SDS)scores were decreased,and the scores were significantly lower in study group than in control group(P<0.01).At 6 months after surgery,the functional assessment of cancer therapy-breast(FACT-B)score was significantly higher in study group than in control group(P<0.01).There was no significant difference in regard to the incidence rate of recurrence,metastasis and adverse events between the two groups(P>0.05).Conclusion The modified radical mastectomy with retention of nipple and areola demonstrates good clinical effect in the treatment of breast cancer and is worthy of clinical use.
作者
齐建国
齐正
丁小勇
QI Jianguo;QI Zheng;DING Xiaoyong(Department of General Surgery,He’nan Xuchang Central South District Hospital,Xuchang 461000,He’nan,China)
出处
《癌症进展》
2020年第14期1482-1484,1491,共4页
Oncology Progress
关键词
乳头乳晕
乳腺癌改良根治术
负性情绪
临床效果
不良反应
nipple-and areola-sparing
modified radical mastectomy for breast cancer
negative emotion
clinical effect
adverse reaction
作者简介
通信作者:齐建国,邮箱:fey8d2@163.com。
