摘要
目的探讨热习服训练对高温、高湿环境中高强度体力活动人群的影响。方法选择2014年8月~2018年8月70名象山社区业余长跑爱好者,参加5 km长跑训练,采用简单随机分组法分为观察组和对照组,每组35例。观察组在训练前进行热习服训练。比较两组白细胞介素-1β(IL-1β)、γ干扰素(IFN-γ)、肿瘤坏死因子-α(TNF-α)、急性生理与慢性健康评分Ⅱ(APACHEⅡ)、格拉斯哥量表评分(GCS)、肌钙蛋白I(cTnI)、尿肌酐(Cr)、肌酸激酶同工酶(CK-MB)水平。记录两组劳力性热射病、多器官功能障碍综合征发生率、器官累及率的发生情况。结果训练前两组IL-1β、IFN-γ、TNF-α水平比较,差异无统计学意义(P>0.05);训练后两组IL-1β、IFN-γ、TNF-α高于训练前,且观察组低于对照组,差异均有统计学意义(均P<0.05)。训练前两组APACHEⅡ、GCS评分水平比较,差异无统计学意义(P>0.05);训练后两组APACHEⅡ评分高于训练前、GCS评分低于训练前,且观察组APACHEⅡ评分低于对照组,GCS评分高于对照组,差异均有统计学意义(均P<0.05);训练前两组cTnI、Cr和CK-MB水平比较,差异无统计学意义(P>0.05);训练后两组cTnI、Cr、CK-MB高于训练前,观察组低于对照组,差异均有统计学意义(均P<0.05)。观察组劳力性热射病、多器官功能障碍综合征、器官累及发生率低于对照组,差异有统计学意义(P<0.05)。结论热习服训练对高温、高湿环境中高强度体力活动人群效果显著,可有效改善炎性反应,减少多器官功能障碍综合征的发生率,值得推广应用。
Objective To explore the effect of heat acclimation training on people with high intensity physical activity in high temperature and humidity environment.Methods From August 2014 to August 2018,70 amateur long-distance runners in Xianshan Community participate in 5 km long-distance training were divided into the oservation group and the control group by simple random grouping method,with 35 in each group.The observation group was received heat acclimation training before training.The changes of interleukin-1β(IL-1β),γinterferon(IFN-γ),tumor necrosis factor-α(TNF-α),acute physiology and chronic health evaluationⅡ(APACHEⅡ),glasgow coma scale(GCS),troponin I(cTnI),urine creatinine(Cr),creatine kinase isoenzymes(CK-MB)level.The incidence of exertional heat stroke,multiple organ dysfunction syndrome and the organ involvement rate in the two groups were compared.Results Before training,there were no significant differences in the levels of IL-1β,IFN-γand TNF-αin the two groups(P>0.05).After training,the IL-1β,IFN-γand TNF-αlevels in the two groups were increased than those before training,and the observation group was lower than the control group,with statistically significant differences(P<0.05).Before training,there were no significant differences in APACHEⅡand GCS scores between the two groups(P>0.05).After training,APACHEⅡscores of the two groups were increased than those before training,GCS scores were decreased than those before training,and APACHEⅡscores of the observation group were lower than those of the control group,and GCS scores were higher than those of the control group,the differences were statistically significant(all P<0.05).Before training,there were no significant differences in cTnI,Cr and CK-MB levels between the two groups(P>0.05).After training,cTnI,Cr and CK-MB levels in the two groups were increased than those before training,the observation group was lower than the control group,with statistically significant differences(all P<0.05).The incidence of exertional heat stroke,multiple organ dysfunction syndrome and organ involvement in the observation group were lower than those in the control group(P<0.05).Conclusion Heat acclimation training has a significant effect on high intensity physical activity in high temperature and high humidity environment.It can effectively improve the inflammatory response and reduce the incidence of multiple organ dysfunction syndrome.It is worth popularizing and applying.
作者
叶建新
林航
穆军山
崔晓萍
俞珠玲
YE Jianxin;LIN Hang;MU Junshan;CUI Xiaoping;YU Zhuling(Department of Neurology,the 900th Hospital of the Joint Service Support Force of the Liberation Army,Fujian Province,Fuzhou350025,China;Fuzong Clinical Medical College of Fujian Medical University,Fujian Province,Fuzhou350025,China)
出处
《中国医药导报》
CAS
2020年第15期22-25,共4页
China Medical Herald
基金
福建省自然科学基金科技项目(2017J01319)。
关键词
劳力性热射病
热习服训练
炎性反应
多器官功能障碍综合征
Exertional heat stroke
Heat acclimation training
Inflammatory response
Multiple organ dysfunction syndrome
作者简介
叶建新(1969.1-),女,硕士,主任医师,研究方向:热射病的临床与基础。
