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辽宁省新型冠状病毒肺炎聚集性病例流行病学分析 被引量:14

Clustering of 2019 novel coronavirus disease cases in Liaoning province:reported data-base analysis
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摘要 目的分析辽宁省新型冠状病毒肺炎聚集性病例的流行特征,为有效控制疫情提供对策、依据和参考。方法采用描述性分析方法对辽宁省新型冠状病毒肺炎聚集性病例进行三间分布、潜伏期以及临床症状进行分析。结果截至2020年2月21日24时,辽宁省共发生聚集性病例26起81例,占总病例数的66.9%,全部为家庭聚集性。聚集性事件分布在10个地级市,聚集规模2~6例/起。30~69岁为聚集性病例高发年龄段,占聚集性病例总数的76.5%;男女比例0.84:1;潜伏期中位数为8.0天。聚集性事件首发病例发病前14天内有湖北旅居史的16例,占61.5%;有湖北以外其它有病例省份旅居史的7例,占26.9%;30.8%(8例)严重程度为重型或危重型。临床表现主要为发热(63.0%)、乏力(24.7%)、干咳(23.5%)、头痛(11.1%)和肌肉酸痛(11.1%)。结论辽宁省聚集性疫情病例以输入为主,控制家庭感染是控制辽宁省新冠肺炎疫情的重点。 Objective To analyze prevalence characteristics of clustering cases of 2019 novel coronavirus disease(COVID-19) in Liaoning province for providing evidences to effective containment of COVID-19 epidemic. Methods We collected the information on all reported COVID-19 cases from the day of first case report(January 22, 2020) till February21, 2020 and analyzed the data with descriptive statistics. Results Among a total of 121 COVID-19 cases reported during the 31 days in Liaoning province, totally 26 epidemic clusters were identified and all the clusters occurred in family settings.The epidemic clusters involved 81 cases in 10 prefecture-level regions, accounting for 66.9% of the all cases reported. For the clusters identified, the number of cases was between 2 and 6 for each cluster. Of all the cluster cases, 76.5% were aged 30 –69 years. For all the cluster cases, the male to female ratio was 0.84 : 1 and the incubation period ranged 1-19 days, with a median of 8.0 days. Of all the initial cases of the clusters, 16(61.5%) reported the history of travelling in Hubei province(the epicenter of COVID-19) within 14 days before the onset of the disease;7(26.9%) reported the history of travelling in other provinces;8(30.8%) were severe or critical severe cases. Main clinical manifestations of the cluster cases were fever(occurred in 63.0% of the cases), fatigue(24.7%), dry cough(23.5%), headache(11.1%), and muscle soreness(11.1%).Conclusion In Liaoning province, the majority of the COVID-19 cluster cases were imported cases and occurred in family settings, suggesting that the control of family transmission of COVID-19 is the key to the containment of the epidemic.
作者 刘莉 井丽 礼彦侠 田园梦 游弋 崔建秋 田疆 邢立莹 杨佐森 LIU Li;JING Li;LI Yan-xia(Liaoning Provincial Center for Disease Control and Prevention,Shenyang,Liaoning Province 110005,China)
出处 《中国公共卫生》 CAS CSCD 北大核心 2020年第4期473-476,共4页 Chinese Journal of Public Health
基金 辽宁省新型冠状病毒感染的肺炎疫情防控应急科研攻关项目(2020JH2/10300001)。
关键词 新型冠状病毒肺炎 流行病学 聚集性病例 辽宁 COVID-19 epidemiology cluster cases Liaoning province
作者简介 刘莉(1980-),女,辽宁省沈阳市,副主任医师,硕士,研究方向:流行病与卫生统计学相关研究工作;通信作者:杨佐森,E-mail:yangzuosen985@126.com。
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