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阿司匹林+氯吡格雷治疗老年冠心病的效果及不良反应观察 被引量:4

Observation on the effect and adverse reactions of aspirin+clopidogrel on senile coronary heart disease
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摘要 目的:评估阿司匹林联合氯吡格雷治疗老年冠心病的效果和不良反应情况。方法:2017年6月-2019年6月收治老年冠心病患者50例,随机分为两组,各25例。试验组采用阿司匹林联合氯吡格雷治疗;对照组运用阿司匹林治疗。比较两组治疗效果。结果:试验组治疗总有效率高于对照组,差异有统计学意义(P<0.05);试验组治疗21 d后氨基末端脑钠尿肽(NT-proBNP)指标水平低于对照组,差异有统计学意义(P<0.05)。结论:老年冠心病患者采取阿司匹林联合氯吡格雷治疗效果良好,且不良反应较少。 Objective:To evaluate the efficacy and adverse reactions of aspirin combined with clopidogrel in the treatment of elderly patients with coronary heart disease.Methods:From June 2017 to June 2019,50 elderly patients with coronary heart disease were enrolled,they were randomly divided into two groups with 25 cases in each group.The experimental group was treated with aspirin combined with clopidogrel.The control group was treated with aspirin.The therapeutic effects between the two groups were compared.Results:The total effective rate of treatment of experimental group was higher than control group,the difference was statistically significant(P<0.05).The indicator level of amino terminal brain natriuretic peptide(NT-proBNP)in experimental group after 21 days treatment was lower than in control group,the difference was statistically significant(P<0.05).Conclusion:Aspirin combined with clopidogrel is effective in the treatment of elderly patients with coronary heart disease effect and it has less adverse reactions.
作者 杨英 Yang Ying(An Zhen Community Health Service Centre of Chaoyang District,Beijing City 100011)
出处 《中国社区医师》 2020年第14期58-58,60,共2页 Chinese Community Doctors
关键词 阿司匹林 氯吡格雷 老年 冠心病 不良反应 Aspirin Clopidogrel Old age Coronary heart disease Adverse reactions
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