摘要
3D打印复合多孔性骨组织工程支架已成为研究热点。复合聚乙烯醇(polyvinyl alcohol,PVA)具备良好生物相容性及可降解性能,但因不能抵抗较大机械抗力,不能单独制备支架,复合其他机械性能佳及生物相容性良好的材料,可表现出良好的生物相容性、可降解性及机械性能等优点,因此3D打印复合PVA支架材料可以优化PVA支架的性能,本文从3D打印骨组织工程支架技术、PVA、复合PVA支架在体内外骨形成效果等方面作一综述。
Three dimensionally printed composite porous bone tissue engineering scaffolds have become a research focus.Composite polyvinyl alcohol(PVA) has good biocompatibilityand degradability,but it cannot be prepared independently because it cannot resist highmechanical resistance.This material shows many advantages,such as good biocompatibility,degradability and mechanical properties,when compounded with other materials with good mechanical properties and good biocompatibility.Therefore,3 D printed composite PVA scaffold material can optimize the performance of PVA scaffolds.This article reviews 3 D printing bone scaffold technology,polyvinyl alcohol(PVA),and composite PVA scaffolds for in vivo and in vitro bone formation.
作者
刘小元
张凯
韩祥祯
左新慧
李君
何惠宇
LIU Xiaoyuan;ZHANG Kai;HAN Xiangzhen;ZUO Xinhui;LI Jun;HE Huiyu(Xinjiang Uygur Autonomous Region Institute of Stomatology,De⁃partment of Prosthodontics,the First Affiliated Hospital(Affiliated Stomatological Hospital)of Xinjiang Medical Uni⁃versity,Urumqi 830054,China)
出处
《口腔疾病防治》
2020年第1期52-55,共4页
Journal of Prevention and Treatment for Stomatological Diseases
基金
国家自然科学基金项目(81660177)
自治区科技支疆项目计划(2018E02060)
关键词
骨缺损
3D打印
光固化成型
选择性激光烧结
熔融层积成型
喷墨印刷
生物墨水
组织工程骨支架
聚乙烯醇
骨形成
bone defect
3D printing
stereo lithography appearance
selective laser sintering
fused deposi⁃tion modeling
ink jet printing
bioink
tissue engineering bone scaffold
polyvinyl alcohol
bone formation
作者简介
刘小元,医师,在读硕士研究生,Email:liuxiaoyu-an0423@126.com;通讯作者:何惠宇,教授,博士,Email:hehuiyu01@126.com,Tel:13079998882。
