期刊文献+

骨组织工程支架研究现状及面临的问题 被引量:16

Research process and problem of bone tissue engineering scaffold
在线阅读 下载PDF
导出
摘要 在理想骨组织工程支架所需满足条件的基础上,从材料的选取、设计、制备等方面就其发展现状做出了简要总结。国内外大量的实验证实了骨组织工程支架缺损修复的可行性、有效性及优越性。然而,目前构建的骨组织工程支架还很不完善,在力学性能、降解速度、结构形态、生物活性等方面仍有许多问题亟待解决。随着骨组织工程及其相关领域研究的深入和进步,骨组织工程支架的研究将会具有突破性的进展。 Based on the requirements of ideal bone tissue engineering scaffold need to meet, this paper briefly summarized bone tissue engineering scaffold from material selection, design and preparation. Many domestic and abroad experiments have confirmed that bone tissue engineering scaffold is feasible, effective and superior in repairing bone tissue defects. However, so far the constructed bone tissue engineering scaffold is far from perfect, some areas, such as the mechanical properties, degradation of speed, structure and biological activity, are still need to be resolved. With further carrying out, the research of bone tissue engineering scaffold will have ground-breaking progress, and it will have a bright future in the clinical applications.
作者 杨春蓉
出处 《中国组织工程研究与临床康复》 CAS CSCD 北大核心 2009年第8期1529-1532,共4页 Journal of Clinical Rehabilitative Tissue Engineering Research
基金 福建工程学院科研启动基金(E060070)~~
作者简介 杨春蓉,女,1977年生,湖北省枝江市人,汉族,2006年华南理工大学材料科学与工程学院毕业,博士,讲师,主要从事生物医用材料方面的研究。lambmeo@163.com
  • 相关文献

参考文献31

  • 1Laurencin CT, EI-Amin SF, Ibim SE, et al. A highly porous 3-dimensional polyphosphazene polymer matrix for skeletal tissue regeneration. J Biomed Mater Res. 1996; 30(2):133-138.
  • 2赵影颖,石润杰.骨与软骨组织工程研究成果的介绍及问题展望[J].中国组织工程研究与临床康复,2008,12(33):6513-6517. 被引量:5
  • 3Langer R, Vacanti JP.Tissue engineering.science. 1993; 260(5110):920-926.
  • 4Hutmacher DW. Scaffolds in tissue engineering bene and cartilage. Biomaterials. 2000; 21 (24):2529-2543.
  • 5Zhang-R, Ma PX. Porous poly(L-iactic acid)/apatite composites created by biomimetic process. J Biomed Mater Res. 1999; 45(4):285-293.
  • 6Ural E, Kesenci K, Fambri LC, et al. Poly(D,L-E-lactic-caprolactone)-hydroxyapatite composite. Biomaterials.2000; 21: 2147-2152.
  • 7Chang BS, Lee CK, Hong KS. Osteoconduction at porous hydroxyapatite with various pore configuration. Biomaterials.2000; 21 (25):1291-1304.
  • 8Thomson RC, Yaszemski M J, Powers JM, et al. Hydroxyapatite fiber reinforced poly(alpha-hydroxy ester) foams for bone regeneration. Biomaterials. 1998; 19(21):1935-1943.
  • 9Devin JE, Attawia MA, Laurencin CT. Three-dimensional degradable porous polymer-ceramic matrices for use in bone repair. J Biomater Sci Polym Ed. 1996; 7(8):661-669.
  • 10Serre CM, Papillard M, Chavassieux P, et al.lnfluence of magnesium substitution on a collagen-apatite biomaterial on the production of a calcifying matrix by human osteoblasts. J Biomed Mater Res. 1998; 42(4):626-633.

二级参考文献87

共引文献301

同被引文献184

引证文献16

二级引证文献62

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部