摘要
目的建立快速鉴别郁金、莪术、姜黄配方颗粒的红外光谱方法。方法采用红外光谱结合二阶导数光谱及二维相关光谱法分析郁金、莪术和姜黄配方颗粒光谱特征。结果不同配方颗粒二阶导数光谱在800~1 800 cm-1范围内差异较大,二维相关光谱图差异明显。结论通过比较红外光谱图、二阶导数光谱图及二维相关光谱图,可以准确、快速鉴别郁金、莪术、姜黄配方颗粒。
Objective To establish a rapid FT-IR method for identifying 3 Formula Granules of Curcumae Radix, Curcuame Rhizoma and Curcumae Longae Rhizoma. Methods FT-IR corresponding second derivative spectra and two-dimensional correlation spectroscopy were applied to analyze the spectral characteristic of Curcumae Radix, Curcuame Rhizoma and Curcumae Longae Rhizoma Formula Granules. Results The second derivative spectra of different Formula Granules were significantly different in the range of 800 - 1 800 cm-1, and the two-dimensional correlation spectra were significantly different. Conclusions By comparing the infrared spectra, second derivative spectra and two-dimensional correlation spectroscopy of different products. It can be identified rapidly and accurately of Curcumae Radix, Curcuame Rhizoma and Curcumae Longae Rhizoma Formula Granules.
作者
冯彩霞
田伟
甄亚钦
修宪
李军山
牛丽颖
FENG Caixia;TIAN Wei;ZHEN Yaqin;XIU Xian;LI Junshan;NIU Liying(The Fifth Hospital of Shijiazhuang,Shijiazhuang 050021,China;Hebei University of Chinese Medicine,Shijiazhuang 050091,China;Hebei TCM Formula Granule Engineering&Technology Research Center,Shijiazhuang 050091,China;The Second Hospital of Shijiazhuang,Shijiazhuang 050051,China)
出处
《药物评价研究》
CAS
2019年第10期1995-2000,共6页
Drug Evaluation Research
基金
石家庄市科技支撑计划（171461293）
关键词
红外光谱法
导数光谱
二维光谱
配方颗粒
infrared spectrum
second derivative spectrum
two-dimensional correlation pectroscopy
Formula Granules
作者简介
第一作者:冯彩霞,女,高级工程师,硕士,研究方向为新药开发。Tel:(0311)85925636 E-mail:fern_yange@163.com;通信作者:牛丽颖,女,教授,研究方向中药质量控制与中药药效物质基础。Tel:(0311)89926548 E-mail:hebeichina@163.com。
