摘要
目的观察中医理筋手法加中药外敷对急性踝关节扭伤患者静脉血超氧化物歧化酶(SOD)及丙二醛(MDA)水平的影响并探讨其作用机制。方法患者80例随机分为两组,对照组仅接受石膏外固定治疗,观察组予中医理筋手法加肿意膏及活血膏外敷治疗,于首诊时、首诊2 d、7 d、14 d后进行视觉模拟量表(VAS)评分,并抽取静脉血查SOD及MDA水平。结果组内比较,对照组首诊14 d后VAS评分较首诊日明显降低(P <0.05),首诊后14 d内SOD水平较首诊日无明显变化(P> 0.05),首诊14 d后静脉血MDA水平较首诊日明显减轻(P <0.05);观察组首诊7 d后、14 d后VAS评分较首诊日明显降低(P <0.05),首诊2 d后、7 d后SOD水平较首诊日明显增高(P <0.05),首诊7 d后、14 d后静脉血MDA水平较首诊日明显减轻(P <0.05);组间比较,观察组首诊7 d后VAS评分明显低于对照组(P <0.05),首诊2 d后、7 d后SOD水平明显高于对照组(P <0.05),首诊7 d后患者静脉血MDA水平明显低于对照组(P <0.05)。结论中医理筋手法加中药外敷能较快缓解急性踝关节扭伤患者的疼痛症状,能升高患者静脉血的SOD水平,降低其MDA水平。
Objective:To observe the effects and mechanism of TCM tendon manipulation combined with external application of TCM on SOD and MDA levels in venous blood of patients with acute ankle sprain. Methods:80 patients were randomly divided into two groups,40 cases in each. The control group was treated with plaster external fixation only,while the experimental group was treated with traditional Chinese medicine tendon manipulation plus Zhongyi Ointment and Huoxue Ointment. VAS was scored at the first visit,2 days,7 days and 14 days after the first visit,and the levels of SOD and MDA were examined by venous blood sampling. Results:On 14 th day after the first visit,the VAS score of the control group was significantly lower than that of the first day(P < 0.05);the level of SOD had no significant change(P > 0.05),and the level of MDA in venous blood was significantly reduced(P < 0.05). The VAS score of the experimental group decreased significantly after 7 days and 14 days of the first visit(P < 0.05);the SOD level increased significantly after 2 days and 7 days of the first visit(P < 0.05),and the MDA level in venous blood decreased significantly after 7 days and 14 days of the first visit(P < 0.05). The VAS score of the experimental group was significantly lower than that of the control group 7 days after the first visit(P < 0.05);the SOD level was significantly higher than that of the control group 2 days and 7 days after the first visit(P < 0.05),and the MDA level of venous blood on 7 th day after the first visit was significantly lower than that of the control group(P < 0.05). Conclusion:TCM tendon manipulation combined with external application of TCM can quickly relieve pain symptoms in patients with acute ankle sprain,increase SOD level of venous blood and reduce MDA level.
作者
姜仁建
蒲萍
曹洪辉
雷鸣
王美元
Jiang Renjian;Pu Ping;Cao Honghui(Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400021,China.)
出处
《中国中医急症》
2019年第8期1408-1410,1437,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
重庆市科委课题(cstc2017jxj1130031)
关键词
急性踝关节扭伤
中医理筋手法
中药外敷
超氧化物歧化酶
丙二醛
Acute ankle sprains
Chinese medicine tendon manipulation
External application of Chinese Medicine
SOD
MDA
作者简介
通信作者:蒲萍,电子邮箱:550387075@qq.com.
