摘要
目的:本研究旨在对醒脑平衡针刺法治疗急性缺血性脑卒中患者的血浆超氧化物歧化酶(SOD)水平及美国国立卫生研究院卒中量表(NIHSS)评分、日常生活活动能力(Modified Barthel Index,MBI)评分进行观察分析,进而从临床、理化方面对其疗效进行评估。方法:选取2014年10月至2016年10月北京市中西医结合医院脑病科住院的急性缺血性脑卒中患者60例作为研究对象,随机分为观察组与对照组,每组30例。观察组予醒脑平衡针刺法治疗,对照组予普通针刺治疗,疗程均为21 d,入院第1天、第21天后抽取血浆测定SOD水平,同时进行NIHSS、MBI量表评定,进行分析归纳。结果:观察组脱落3例,纳入27例,对照组脱落5例,纳入25例。第1天2组患者SOD、NIHSS评分和MBI评分差异无统计学意义( P >0.05);治疗21 d后,2组患者血浆SOD水平较第1天明显升高,差异有统计学意义( P <0.05),其中观察组较对照组升高明显,差异有统计学意义( P <0.05);治疗21 d后观察组NIHSS评分低于对照组,差异有统计学意义( P <0.05);治疗21天后观察组MBI评分高于对照组,差异有统计学意义( P <0.05)。结论:醒脑平衡针刺法治疗急性脑梗死患者能明显改善患者神经功能缺损程度,提高日常活动能力,同时能提高患者血浆SOD水平。针刺治疗急性缺血性脑卒中患者血浆SOD水平明显升高,血浆SOD水平可从一定程度上作为针灸治疗急性缺血性脑卒中的疗效指标。
Objective: The purpose of this study was to observe and analyze the plasma SOD level,NIHSS score and MBI score of patients with acute ischemic stroke treated with Xingnao Pingheng acupuncture,and to evaluate its curative effect from clinical and physicochemical aspects. Methods: Sixty patients with acute ischemic stroke admitted to the Department of Encephalopathy,Beijing Hospital of Integrated Traditional Chinese and Western Medicine from October 2014 to October 2016 were selected as subjects.They were randomly divided into an observation group and a control group,with 30 cases in each group.The observation group was treated with Xingnao Pingheng acupuncture,and the control group was treated with ordinary acupuncture.The course of treatment was 21 days.On the first day and 21 days after admission,the levels of SOD in plasma were measured,and NIHSS and MBI were evaluated in the acute cerebral infarction group. Results: The observation group had 3 patients falling off,27 patients were enrolled;5 patients were lost in t the control group,25 patients were enrolled;There was no significant difference in SOD,NIHSS score and MBI score between the two groups on the first day( P >0.05).After 21 days of treatment,the plasma SOD levels of the two groups were significantly higher than those of the first day( P <0.05),and the observation group was significantly higher than the control group,the difference was statistically significant( P <0.05).The NIHSS score of the observation group was lower than that of the control group after 21 days of treatment,and the difference was statistically significant( P <0.05).The MBI score of the observation group was higher than that of the control group after 21 days of treatment,he difference was statistically significant( P <0.05). Conclusion: XingnaoPingheng acupuncture treatment of acute cerebral infarction can significantly improve the degree of neurological deficit,improve ability of daily activities,and improve plasma SOD levels.The level of SOD in plasma of patients with acute ischemic stroke was significantly increased by acupuncture treatment.Plasma SOD level can be used as a therapeutic index for acupuncture treatment of acute ischemic stroke to a certain extent.
作者
武晓磊
冯学功
Wu Xiaolei;Feng Xuegong(Department of Encephalopathy,Beijing Hospital of Integrated Tranditional and Western Medicine,Beijing 100039,China)
出处
《世界中医药》
CAS
2019年第6期1577-1580,1585,共5页
World Chinese Medicine
基金
北京中医药科技发展基金项目(JJ2015-19)
作者简介
武晓磊(1980.08—),男,硕士,主治医师,研究方向:脑病防控,E-mail:wxlbjzxyjh@163.com.
