摘要
目的:探讨醒脑静注射液联合软通道微创血肿引流术治疗高血压性脑出血的疗效。方法:选取2014年6月至2018年6月江西省宜丰县人民医院收治的高血压性脑出血患者50例,以随机数字表法分为观察组和对照组,每组25例。对照组患者给予软通道微创血肿引流术治疗,观察组患者给予醒脑静注射液联合软通道微创血肿引流术治疗。比较两组患者脑血肿体积、日常生活能力(activities of daily living,ADL)评分及临床疗效的差异。结果:治疗7、14 d后,观察组患者的脑血肿体积明显小于对照组,差异有统计学意义(P<0.05);治疗后,观察组、对照组患者平均ADL评分分别为(69.8±6.3)、(67.1±6.0)分,均明显优于本组治疗前,且观察组患者明显优于对照组,差异均有统计学意义(P<0.05);观察组、对照组患者的总有效率分别为88%(22/25)、80%(20/25),差异无统计学意义(P>0.05)。结论:醒脑静注射液联合软通道微创血肿引流术治疗高血压性脑出血,可加快血肿的清除,减轻对神经功能的损害,提高生活质量,改善预后。
OBJECTIVE:To probe into the efficacy of Xingnaojing injection combined with soft-channel minimally invasive hematoma drainage in treatment of hypertensive cerebral hemorrhage.METHODS:50patients with hypertensive cerebral hemorrhage admitted into Jiangxi Yifeng County People’s Hospital from Jun.2014to Jun.2018were selected and divided into observation group and control group via random number table,with25cases in each.Differences in volumes of hematoma,scores of activities of daily living(ADL)and clinical efficacy between two groups were compared.RESULTS:After7-day and14-day treatments,the volume of hematoma of observation group was significantly smaller than that of the control group,with statistically significant difference(P<0.05);after treatment,the average ADL scores of observation group and control group were respectively(69.8±6.3)points and(67.1±6.0)points,both were better than those of before treatment,and that of observation group was significantly better than the control group,with statistically significant differences(P<0.05);the total effectively rates of observation group and control group were respectively88%(22/25)and80%(20/25),the difference had no statistical significance(P>0.05).CONCLUSIONS:The combination of Xingnaojing injection and soft-channel minimally invasive hematoma drainage in treatment of hypertensive cerebral hemorrhage can accelerate the removal of hematoma,reduce the damage of neurological function,promote the quality of life and improve the prognosis.
作者
江砚明
肖伟鑫
JIANG Yanming;XIAO Weixin(Dept.of Internal Medicine, Jiangxi Yifeng County People’s Hospital,Jiangxi Yifeng336300,China)
出处
《中国医院用药评价与分析》
2018年第11期1495-1496,1499,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
醒脑静注射液
软通道微创血肿引流术
高血压性脑出血
Xingnaojing injection
Soft-channel minimally invasive hematoma drainage
Hypertensive cerebral hemorrhage
作者简介
江砚明,主治医师。研究方向:内科消化疾病。E-mail:1025767479@qq.com
