摘要
目的分析中药心脑血脉宁联合他汀类药物对脑梗死患者颈动脉粥样硬化斑块的影响。方法选取180例脑梗死患者并按随机数字表法分为观察组（90例）与对照组（90例），对照组给予阿托伐他汀钙片，观察组联合心脑血脉宁，分别于治疗前后对患者颈动脉粥样硬化斑块的变化情况、预后进行评价，并统计不良反应发生率。结果治疗前2组颈动脉粥样硬化斑块及中医症候积分、神经功能缺损评分对比无差异；治疗后上述指标均显著改善，且观察组改善幅度优于对照组；同时，观察组不良反应发生率（5.56%）低于对照组（13.33%）,差异具有统计学意义（P＜0.05）。结论心脑血脉宁能减少脑梗死患者颈动脉粥样硬化斑块面积，纠正不稳定性斑块。
Objective To investigate the effects of Xinnaoxuemianning combined with statins on carotid atherosclerotic plaque in patientswith cerebral infarction.Methods180cerebral infarction patients were divided into the observation group(90cases)and the control group(90cases)by random number table method.The control group was given atorvastatin calcium tablets and the observation group was given additionallyXinnaoxuemianning.The changes and prognosis of carotid atherosclerotic plaques were evaluated before and after treatment,and the incidence ofadverse reactions was counted.Results There were no differences in the carotid atherosclerotic plaque,TCM syndrome score and neurological deficitseverity between the two groups before treatment.After treatment,the above indexes were significantly improved,and the increasing degree of theobservation group was better than that of the control group.The incidence rate of adverse reactions was lower in the observation group than that inthe control group(5.56%vs.13.33%)(P<0.05).Conclusion Xinnaoxuemianning can reduce the carotid atherosclerotic plaque area and correct theunstable plaques in patients with cerebral infarction.
作者
沈卫
林东
SHEN Wei;LIN Dong(Pepartment of Pharmacy, Pingyang First People's Hospital, Wenzhou 325400, China;Department of Traditional Chinese Medicine, Pingyang Traditional Chinese Medicine, Wenzhou 325400, China)
出处
《中国生化药物杂志》
CAS
2017年第9期65-66,69,共3页
Chinese Journal of Biochemical Pharmaceutics
作者简介
沈卫，通信作者，女，本科，主管中药师，研究方向：活血化瘀中药药理作用，E-mail：ysshenwei16@126.com
